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| Product | Description | |
|---|---|---|
| 2',3'-cGAMP | 2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes). Group: Pharmaceutical. Alternative Names: Cyclic [G(2',5')pA(3',5')p]; 2'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-Cyclic guanosine adenosine monophosphate; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate; 2'-3'-cyclic GMP-AMP; cGAMP(2'→5'); c[G(2',5')pA(3',5')p]; Cyclic Gp(2'→5')Ap(3'→5'). CAS No. 1441190-66-4. Pack Sizes: 1 mg. Product ID: B1370-006099. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2'3'-cGAMP photo affinity probe | 2'3'-cyclic GMP-AMP (2'3'-cGAMP), generated by cyclic GMP-AMP synthase (cGAS) under activation by cytosolic DNA, has a vital role in innate immune response via its receptor protein stimulator of interferon genes (STING) to fight viral infections and tumors. 2'3'-cGAMP-based photoaffinity probes can capture and isolate 2'3'-cGAMP-binding proteins. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-099265. Custom synthesis is available. Send your inquiries for more information. | London |
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