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| Product | Description | |
|---|---|---|
| A2ti-1 | A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. Group: Pharmaceutical. Alternative Names: Acetamide, 2-[[4-(2-ethylphenyl)-5-[(2-methylphenoxy)methyl]-4H-1,2,4-triazol-3-yl]thio]-; 2-({4-(2-Ethylphenyl)-5-[(2-methylphenoxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide. CAS No. 570390-00-0. Pack Sizes: 10 mg. Product ID: B1370-060255. Molecular formula: C20H22N4O2S. Mole weight: 382.48. Custom synthesis is available. Send your inquiries for more information. |  London |
| A2ti-2 | A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 230 μM. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. Group: Pharmaceutical. Alternative Names: 2-{5-[(2-methylphenoxy)methyl]-4-phenyl-1,2,4-triazol-3-ylthio}acetamide; Acetamide, 2-[[5-[(2-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl]thio]-; 2-({5-[(2-Methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide. CAS No. 482646-13-9. Pack Sizes: 100 mg. Product ID: B1370-382474. Molecular formula: C18H18N4O2S. Mole weight: 354.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Inclisiran | Inclisiran is a medication approved for the treatment of people with atherosclerotic cardiovascular disease (ASCVD), ASCVD risk equivalents and heterozygous familial hypercholesterolemia (HeFH). It is a small interfering RNA (siRNA) that binds to PCSK9 messenger RNA, resulting in decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol. Group: Pharmaceutical. Alternative Names: ALN-PCSsc; ALN-60212; Leqvio; Inclisiran sodium; ALN-PCS; Leqvio; RNA, (Am-sp-(2'-deoxy-2'-fluoro)C-sp-Am-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Um-Am-Gm-sp-Am-sp-Am), complex with RNA (Cm-sp-Um-sp-Am-Gm-Am-Cm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Um-dT-Um-Um-Gm-Cm-Um-Um-Um-Um-Gm-Um) 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1). CAS No. 1639324-58-5. Pack Sizes: 5 mg. Product ID: B1370-057828. Molecular formula: C529H707F12N176O316P43S6. Mole weight: 16339.48. Custom synthesis is available. Send your inquiries for more information. | London |
| PT-2385 | PT-2385 is a small molecule inhibitor with oral activity that inhibits hypoxia inducible factor (HIF)-2alpha heterodimerization and its subsequent binding to DNA by binding to HIF-2alpha. Group: Pharmaceutical. Alternative Names: 3-[[(1S)-2,2-difluoro-1-hydroxy-7-methylsulfonyl-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrilePT-2385; PT2385; PT 2385SCHEMBL165558103-{[(1s)-2,2-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1h-Inden-4-Yl]oxy}-5-Fluorobenzonitrile79A. CAS No. 1672665-49-4. Pack Sizes: 10 mg. Product ID: B2693-474658. Molecular formula: C17H12F3NO4S. Mole weight: 383.34. Custom synthesis is available. Send your inquiries for more information. | London |
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