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| Product | Description | |
|---|---|---|
| 1,2,3,4-Tetrahydronaphthalene | 1,2,3,4-Tetrahydronaphthalene. CAS No. 119-64-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| Cycloolivil | Cycloolivil isolated from the herbs of Maytenus hookeri Loes. Uses: Antioxidant. Group: Pharmaceutical. Alternative Names: (1S)-1α-(3-Methoxy-4-hydroxyphenyl)-3,7-dihydroxy-6-methoxy-1,2,3,4-tetrahydronaphthalene-2β,3α-bismethanol;(2S)-2,3α-Bis(hydroxymethyl)-4β-(3-methoxy-4-hydroxyphenyl)-7-methoxytetralin-2α,6-diol. CAS No. 3064-5-9. Pack Sizes: 5 mg. Product ID: NP4107. Molecular formula: C20H24O7. Mole weight: 376.4. Custom synthesis is available. Send your inquiries for more information. |  London |
| Lyoniresinol | Lyoniresinol, a natural lignan isolated from the root of Vitex negundo,is one of the eight lignans purified from methanol which has robust tyrosinase inhibitory capacity. Lyoniresinol exhibits the activity of antioxidative, and it decreases tyrosinase activity and melanin biosynthesis in B16F10 cells by activating ERK signaling, which downregulates MITF, tyrosinase, but not TRP-1 and TRP-2 protein expression, it can perhaps be incorporated into clinical dermatologic use as a skin lightening agent. Uses: Anti-melanogenic; anti-oxidant. Group: Pharmaceutical. Alternative Names: (1S)-1α-(3,5-Dimethoxy-4-hydroxyphenyl)-6,8-dimethoxy-7-hydroxy-1,2,3,4-tetrahydronaphthalene-2β,3α-dimethanol. CAS No. 14464-90-5. Pack Sizes: 1 mg. Product ID: NP3922. Molecular formula: C22H28O8. Mole weight: 420.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 3,4-Dihydro-8-methylnaphthalen-1(2H)-one | 3,4-Dihydro-8-methylnaphthalen-1(2H)-one. Group: Pharmaceutical. Alternative Names: 8-Methyl-1-tetralone; 1(2H)-Naphthalenone, 3,4-dihydro-8-methyl-; 8-methyl-1,2,3,4-tetrahydronaphthalen-1-one. CAS No. 51015-28-2. Pack Sizes: 1 g. Product ID: B1370-024370. Molecular formula: C11H12O. Mole weight: 160.21. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317491 | A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Group: Pharmaceutical. Alternative Names: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. CAS No. 475205-49-3. Pack Sizes: 1mg;1g;10g. Product ID: 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A 80426 | A 80426 is a potent α2-adrenoceptor antagonist and a selective 5-HT uptake inhibitor (Ki = 2.01 and 3.77 nM, respectively). It displays low affinity for a panel of structurally homologous GPCRs. Group: Pharmaceutical. Alternative Names: A-80426; A80426; (R)-2-(Benzofuran-6-yl)-N-((5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)-N-methylethanamine. CAS No. 152148-63-5. Pack Sizes: 1mg;1g;10g. Product ID: 152148-63-5. Molecular formula: C23H27NO2. Mole weight: 349.5. Custom synthesis is available. Send your inquiries for more information. | London |
| ARV-471 | ARV-471, an oral estrogen receptor PROTAC protein degrader for the treatment of breast cancer, is an heterobifunctional molecule that promotes the interaction between estrogen receptor alpha and intracellular E3 ligase complexes. It leads to ubiquitylation and subsequent degradation of estrogen receptors through the proteasome. In ER positive breast cancer cell lines, it has a strong ability to degrade ER with a half-maximal degradation concentration (DC50) of ~2 nM. Group: Pharmaceutical. Alternative Names: ARV471; ARV 471; (S)-3-(5-(4-((1-(4-((1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione; 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-, (3S)-; Vepdegestrant; (3S)-3-[1,3-Dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-2,6-piperidinedione. CAS No. 2229711-68-4. Pack Sizes: 5 mg. Product ID: B1370-380753. Molecular formula: C45H49N5O4. Mole weight: 723.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Dasotraline hydrochloride | Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50 = 4, 6, and 11 nM, respectively). Group: Pharmaceutical. Alternative Names: (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride; SEP-225,289; SEP225,289; SEP225,289; SEP-225289; SEP225289; SEP225289;; Dasotraline; Dasotraline HCl; Dasotraline hydrochloride. CAS No. 675126-08-6. Pack Sizes: 5 mg. Product ID: B0084-241506. Molecular formula: C16H16Cl3N. Mole weight: 328.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Difethialone | Difethialone is an anticoagulant used as an rodenticide. Group: Pharmaceutical. Alternative Names: 3-[3-[4-(4-bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-hydroxythiochromen-4-one. CAS No. 104653-34-1. Pack Sizes: 1mg;1g;10g. Product ID: 104653-34-1. Molecular formula: C31H23BrO2S. Mole weight: 539.487. Custom synthesis is available. Send your inquiries for more information. | London |
| Nepicastat HCl | Nepicastat hydrochloride (SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase that catalyzes the conversion of dopamine to norepinephrine. Nepicastat hydrochloride shows the selective and concentration-dependent inhibition effects on bovine and human dopamine-beta-hydroxylase activity in vitro. In vivo, Nepicastat hydrochloride increases dopamine content and dopamine/noradrenaline ratio in a dose-dependent manner. Nepicastat hydrochloride also produces the similar effects on noradrenaline, dopamine and dopamine/noradrenaline ratio in tissues and plasma of beagle dogs. Nepicastat is currently in Phase II clinical trials in patients with Posttraumatic Stress Disorder. Uses: Nepicastat is currently in phase ii clinical trials in patients with posttraumatic stress disorder. Group: Pharmaceutical. Alternative Names: N6022; N 6022; N-6022; Nepicastat hydrochloride; (S)-5-(aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1H-imidazole-2(3H)-thione hydrochloride; Nepicastat (hydrochloride); UNII-3WK068D17I. CAS No. 170151-24-3. Pack Sizes: 50 mg. Product ID: B0084-453616. Molecular formula: C14H16ClF2N3S. Mole weight: 331.81. Custom synthesis is available. Send your inquiries for more information. | London |
| Nitroso-sertraline-[d3] (cis racemic mixture) | Nitroso-sertraline-[d3] (cis racemic mixture) is a labelled analogue of nitroso-sertraline. Nitroso-sertraline is undergoing extensive first-pass metabolism by cytochrome P450 and selectively inhibits the reuptake of serotonin at the presynaptic neuronal membrane that is used to treat the major depressive disorder, a social anxiety disorder. Group: Pharmaceutical. Alternative Names: N-((1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(methyl-d3)nitrous amide; Nitroso-sertraline-d3 (cis racemic mixture). Pack Sizes: 10 mg. Product ID: BLP-014819. Molecular formula: C17H13D3Cl2N2O. Mole weight: 338.25. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Nitroso Sertraline-[d3] | N-Nitroso Sertraline-[d3] is a deuterated compound of N-Nitroso Sertraline. N-Nitroso Sertraline is an impurity of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat certain mental disorders. Group: Pharmaceutical. Alternative Names: N-((1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(methyl-d3)nitrous amide. Pack Sizes: 10 mg. Product ID: BLP-015173. Molecular formula: C17H13D3Cl2N2O. Mole weight: 338.25. Custom synthesis is available. Send your inquiries for more information. | London |
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