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1,2,3,4-tetrahydroisoquinoline. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 91-21-4. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: tetrahydroisoquinoline.
Methyl 1,2,3,4-tetrahydroisoquinoline-4-carboxylate hydrochloride. Group: Pharmaceutical. Alternative Names: Methyl 1,2,3,4-tetrahydroisoquinoline-4-carboxylate HCl; 4-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, methyl ester, hydrochloride (1:1). CAS No. 1171535-51-5. Pack Sizes: 1 g. Product ID: BB077789. Molecular formula: C11H14ClNO2. Mole weight: 227.69. Custom synthesis is available. Send your inquiries for more information.
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Lifitegrast
Lifitegrast is a Lymphocyte Function-Associated Antigen-1 (LFA-1) antagonist. It is used for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins, thus lessening overall inflammatory responses. It was initially developed by SARcode Bioscience, which was acquired by Shire in 2013. Group: Pharmaceutical. Alternative Names: SAR-1118; SAR 1118; SAR1118; Xiidra; L-Phenylalanine, N-[[2-(6-benzofuranylcarbonyl)-5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl]carbonyl]-3-(methylsulfonyl)-; N-[[2-(6-Benzofuranylcarbonyl)-5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl]carbonyl]-3-(methylsulfonyl)-L-phenylalanine; (2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid; (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid. CAS No. 1025967-78-5. Pack Sizes: 500 mg. Product ID: B0084-474974. Molecular formula: C29H24Cl2N2O7S. Mole weight: 615.48. Custom synthesis is available. Send your inquiries for more information.
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Quinapril EP Impurity A
An intermediate of quinfamide, an anti-amebic agent used to treat tropical parasitic infections. Group: Pharmaceutical. Alternative Names: Tic-OH; (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid; L-Porretine; L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid; H-TIC-OH; (S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid; 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, (3S)-; Tic OH. CAS No. 74163-81-8. Pack Sizes: 1mg;1g;10g. Product ID: BAT-007766. Molecular formula: C10H11NO2. Mole weight: 177.2. Custom synthesis is available. Send your inquiries for more information.
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A-317567
Acid Sensing Ion Channels (ASICs) are a group of sodium-selective ion channels that are activated by low extracellular pH. A-317567 is a novel non-amiloride blocker. Group: Pharmaceutical. Alternative Names: A317567; 6-{2-[2-methyl-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]cyclopropyl}naphthalene-2-carboximidamide. CAS No. 371217-32-2. Pack Sizes: 1mg;1g;10g. Product ID: 371217-32-2. Molecular formula: C27H31N3. Mole weight: 397.56. Custom synthesis is available. Send your inquiries for more information.
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Cisatracurium Besilate EP Impurity F
An impurity of Cisatracurium besilate. Atracurium besilate is a non-depolarizing neuromuscular blocking drug (NMBD). Group: Pharmaceutical. Alternative Names: cis-Quaternary Alcohol; Atracurium Impurity D2; (R)-Laudanosine N-3-((5-Hydroxypentyl)oxy)-3-oxopropyl Benzenesulfonate; (1R,2R)-1-(3,4-Dimethoxybenzyl)-2-(3-((5-hydroxypentyl)oxy)-3-oxopropyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium Benze. CAS No. 1100676-16-1. Pack Sizes: 5 mg. Product ID: B0371-467031. Molecular formula: C35H47NO10S. Mole weight: 673.82. Custom synthesis is available. Send your inquiries for more information.
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Cis-Quaternary Acid
An impurity of Cisatracurium besilate. Atracurium besilate is a non-depolarizing neuromuscular blocking drug (NMBD). Group: Pharmaceutical. Alternative Names: 3-((1R,2R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-2-yl)propanoate. CAS No. 1075727-04-6. Pack Sizes: 5 mg. Product ID: B0371-007237. Molecular formula: C24H31NO6. Mole weight: 429.52. Custom synthesis is available. Send your inquiries for more information.
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(-)-CorluMine
(-)-Corlumine is a natural alkaloid compound found in some plant. Group: Pharmaceutical. Alternative Names: (S)-6-((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)-[1,3]dioxolo[4,5-e]isobenzofuran-8(6H)-one. CAS No. 79082-64-7. Pack Sizes: 1 mg. Product ID: NP0103. Molecular formula: C21H21NO6. Mole weight: 383.39. Custom synthesis is available. Send your inquiries for more information.
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EPZ015866
EPZ015866,also called as GSK591, is a chemical probe for PRMT5 which has a role in diverse cellular processes including tumorigenesis. It exhibits excellent selectivity against a panel of methyltransferases. Inhibits the PRMT5/MEP50 complex from methylati. Group: Pharmaceutical. Alternative Names: GSK591; GSK-591; GSK 591; EPZ015866; EPZ-015866; EPZ 015866; GSK 3203591; GSK-3203591; GSK3203591; 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamideEPZ015866GSK591GTPL8954SCHEMBL16220740GSK32035912-(cyclobutylamino)-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyridine-4-carbo. CAS No. 1616391-87-7. Pack Sizes: 300 mg. Product ID: B0084-474632. Molecular formula: C22H28N4O2. Mole weight: 380.48. Custom synthesis is available. Send your inquiries for more information.
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Tenapanor
This active molecular is an sodium-proton exchanger NHE3 inhibitor under the development of Ardelyx. This antiporter protein plays a really important role in sodium handling in the gastrointestinal tract and kidney and it regulates the levels of sodium absorbed and secreted by the body. Therefore, tenapanor can be useful in the treatment of chronic kidney disease and hypertension because both of them are exacerbated by excess sodium in the diet. In Oct 2016, Phase-III clinical trials in Hyperphosphataemia (in patients with end-stage renal disease) in USA was on going. Uses: Hyperphosphataemia. Group: Pharmaceutical. Alternative Names: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide; AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor free base. CAS No. 1234423-95-0. Pack Sizes: 25 mg. Product ID: B0084-475197. Molecular formula: C50H66Cl4N8O10S2. Mole weight: 1145.04. Custom synthesis is available. Send your inquiries for more information.
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Tenapanor HCl
Tenapanor, also known as AZD-1722 and RDX 5791, is a first-in-class, small-molecule inhibitor of the gastrointestinal sodium/hydrogen exchanger NHE3. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Tenapanor acts in the gastrointestinal tract to reduce the absorption of sodium and phosphate, with minimal systemic drug exposure. Group: Pharmaceutical. Alternative Names: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide dihydrochloride; AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor; Tenapanor hydrochloride; Tenapanor dihydrochloride. CAS No. 1234365-97-9. Pack Sizes: 50 mg. Product ID: B2693-007851. Molecular formula: C50H68Cl6N8O10S2. Mole weight: 1217.9. Custom synthesis is available. Send your inquiries for more information.
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