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(R)-alpha-Lipoic Acid, a vitamin-like organosulfur compound, is widely used as a dietary supplement and antioxidant. It has been also found to influence the activity of nuclear factor kappa-B (NF-κB). Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: (R)-lipoic acid; (+)-alpha-Lipoic acid; (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid; R-(+)-alpha-Lipoic acid; 5-[(3R)-dithiolan-3-yl]pentanoic acid. CAS No. 1200-22-2. Pack Sizes: 25 g. Product ID: B0084-359920. Molecular formula: C8H14O2S2. Mole weight: 206.318. Custom synthesis is available. Send your inquiries for more information.
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Sodium (R)-alpha-lipoate
Sodium (R)-alpha-lipoate, a robust antioxidant, is efficaciously exploited to rectify diabetic neuropathy. By enhancing glucose metabolism and curtailing oxidative stress, sodium (R)-alpha-lipoate averts nerve damage. Additionally, research illustrates its prospective role in remedying Alzheimer's disease and multiple sclerosis. Group: Pharmaceutical. Alternative Names: Sodium (R)-lipoate; 1,2-Dithiolane-3-pentanoic acid, sodium salt, (R)-; Sodium (R)-5-(1,2-dithiolan-3-yl)pentanoate; 1,2-Dithiolane-3-pentanoic acid, sodium salt, (3R)- (1:1); (R)-lipoic acid sodium salt; R-(+)-alpha-Lipoic acid sodium salt. CAS No. 176110-81-9. Pack Sizes: 5 g. Product ID: B0001-254721. Molecular formula: C8H13NaO2S2. Mole weight: 228.31. Custom synthesis is available. Send your inquiries for more information.
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CPI-613
CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Although the exact mechanism of action is unknown, alpha-lipoic acid analogue CPI-613 has been shown to inhibit metabolic and regulatory processes required for cell growth in solid tumors. Both enantiomers in the racemic mixture exhibit antineoplastic activity. The mechanism-of-action of CPI-613 appears distinct from the current classes of anti-cancer agents used in the clinic. CPI-613 demonstrates both in vitro and in vivo anti-tumor activity. CPI-613 was known to strongly disrupt tumor mitochondrial metabolism. CPI-613 disruption of tumor mitochondrial metabolism is followed by efficient commitment to cell death by multiple, apparently redundant pathways, including apoptosis, in all tested cancer cell lines. Further, CPI-613 shows strong antitumor activity in vivo against human non-small cell lung and pancreatic cancers in xenograft models with low side-effect toxicity. Group: Pharmaceutical. Alternative Names: CPI613; CPI 613; Devimistat; 6,8-bis(benzylthio)octanoic acid. CAS No. 95809-78-2. Pack Sizes: 250 mg. Product ID: B1370-103006. Molecular formula: C22H28O2S2. Mole weight: 388.59. Custom synthesis is available. Send your inquiries for more information.
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DL-Thioctic acid
Lipoic acid is a very excellent natural antioxidant, with free radical scavenging effect, its ability to remove free radicals is more than 100 times that of vitamin C, especially suitable for anti-aging products. It has the effect of chelating metal ions, can bind to copper ions in tyrosinase, is a competitive inhibitor of tyrosinase, and has good whitening effect. However, lipoic acid has the problems of low solubility, poor stability and significant odor, which limits its application in cosmetics. The shortcomings of lipoic acid can be solved by supramolecular inclusion technology. It can be widely used in anti-aging, wrinkle removal, whitening, spot lightening, anti-inflammatory and anti-sensitivity, acne treatment, scar reduction, damage repair and other products, and it is compatible with lotion cream formula, gel formula and water formula. Group: Pharmaceutical. Alternative Names: Thioctic acid; alpha-Lipoic acid; (+/-)-2-dithiolane-3-pentanoic acid; 1,2-Dithiolane-3-pentanoic acid; (RS)-Lipoic acid; (RS)-α-Lipoic acid; 5-(1,2-Dithiolan-3-yl)pentanoic acid. CAS No. 1077-28-7. Pack Sizes: 1 kg. Product ID: NP4270. Molecular formula: C8H14O2S2. Mole weight: 206.32. Custom synthesis is available. Send your inquiries for more information.
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Thioctate trometamol
Thioctate trometamol, a derivative of alpha-lipoic acid, displays potent antioxidant effects that aid in the management of diabetic neuropathy, alcoholic liver disease, and associated ailments. By boosting glucose metabolism and mitigating oxidative stress, this pharmaceutical compound facilitates the restoration of metabolic homeostasis. Conventionally available in tablet form for oral administration, Thioctate trometamol boasts excellent patient tolerance. Its striking antioxidant attributes are infinitely promising for disease mitigation in diverse clinical settings. Group: Pharmaceutical. Alternative Names: Dexlipotam; Thioctic acid tromethamine; 5-(1,2-Dithiolaln-3-yl)-pentanoic acid tromethamine; Lipoic Acid Tromethamine Salt; 1,2-Dithiolane-3-pentanoic acid, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1). CAS No. 14358-90-8. Pack Sizes: 1 g. Product ID: B0001-084077. Molecular formula: C8H14O2S2.C4H11NO3. Mole weight: 327.46. Custom synthesis is available. Send your inquiries for more information.
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