(3s,4r)-tofacitinib Suppliers UK

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(3S,4R)-Tofacitinib (3S,4R)-Tofacitinib is a less active enantiopure stereoisomer of the JAK3 inhibitor Tofacitinib. Group: Pharmaceutical. Alternative Names: Tofacitinib Impurity B; 3-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile. CAS No. 1092578-48-7. Pack Sizes: 2.5 mg. Product ID: B2694-463516. Molecular formula: C16H20N6O. Mole weight: 312.27. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. Alternative Names: (3S,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine. CAS No. 1638499-33-8. Pack Sizes: 25 mg. Product ID: B2694-111800. Molecular formula: C14H22N2. Mole weight: 218.34. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Upadacitinib Upadacitinib is a selective JAK inhibitor under the development of AbbVie.ABT-494 is nearly 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Preliminary evidence suggests that ABT-494 may spare Jak2 and Jak3 dependent signaling compared to tofacitinib. Phase II for the treatment of Atopic dermatitis and Crohn's disease, Phase III for the treatment of Rheumatoid arthritis and Ulcerative colitis was on-going. Uses: Rheumatoid arthritis; ulcerative colitis;atopic dermatitis; crohn's disease. Group: Pharmaceutical. Alternative Names: UNII-4RA0KN46E0;ABT494;(3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide. CAS No. 1310726-60-3. Pack Sizes: 5 mg. Product ID: B0084-475295. Molecular formula: C17H19F3N6O. Mole weight: 380.37. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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