BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Micafungin Open-Ring Analog Sodium salt | Micafungin Open-Ring Analog Sodium salt is an impurity of Micafungin, an echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Group: Pharmaceutical. CAS No. 539823-82-0. Pack Sizes: 10 mg. Product ID: B1370-071106. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Micafungin Serine Analog | An impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Group: Pharmaceutical. CAS No. 1392514-04-3. Pack Sizes: 1 mg. Product ID: 1392514-04-3. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Micafungin sodium | Micafungin Sodium is an inhibitor of 1,3-beta-D-glucan synthesis, used as an antifungal drug. Group: Pharmaceutical. CAS No. 208538-73-2. Pack Sizes: 250 mg. Product ID: BAT-010108. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Micafungin Sodium Impurities | Micafungin Sodium Impurities are critical in quality control for antifungal treatments, predominantly micafungin. Monitoring these impurities ensures the efficacy and safety of micafungin, used against various fungal infections such as candidiasis and aspergillosis, maintaining stringent pharmaceutical standards during production. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Micafungin Sodium Stereoisomer | Micafungin Impurity H is an impurity of Micafungin, an echinocandin antifungal drug used for the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Micafungin inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Group: Pharmaceutical. CAS No. 1686155-92-9. Pack Sizes: 1 mg. Product ID: B2694-292566. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miconazole Impurities | Miconazole Impurities, crucial components within the pharmaceutical realm, function as analytical benchmarks in antifungal drug quality control. They enable precise identification and quantification of active ingredients, thereby safeguarding the therapeutic efficacy and safety of treatments for fungal ailments, including athlete's foot, jock itch, and candidiasis, thus advancing clinical pharmacology. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Microcrystalline Cellulose and Carboxymethylcellulose Sodium | Microcrystalline Cellulose and Carboxymethylcellulose Sodium. Group: Pharmaceutical. CAS No. 51395-75-6. Pack Sizes: 1 kg. Product ID: B1370-277638. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Micromelin | Micromelin is isolated from the herbs of Micromelum integerrimum. Uses: Anti-tumor; anti-cancer. Group: Pharmaceutical. CAS No. 15085-71-9. Pack Sizes: 5 mg. Product ID: NP1028. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Midecamycin Impurities | Midecamycin Impurities are indispensable in the intricate realm of macrolide antibiotic analysis, ensuring thorough characterization and quality assessment of Midecamycin. Predominantly targeting bacterial pathogens like Streptococcus and Staphylococcus, these impurities are crucial in affirming the pharmaceutical formulations' efficacy and safety, safeguarding therapeutic standards in medical treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| midodrine hydrochloride | A phenylalkanolamine derivative which has been found to be effective in treating hypertensive conditions due to their long lasting blood pressure increasing effects. Group: Pharmaceutical. CAS No. 3092-17-9. Pack Sizes: 1 g. Product ID: B2692-065717. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Midodrine Impurities | Midodrine Impurities are crucial in pharmaceutical quality control, ensuring the purity and efficacy of midodrine, a medication used to treat orthostatic hypotension. By identifying and characterizing these impurities, researchers can enhance the safety and therapeutic effectiveness of midodrine, contributing to more effective patient management. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Midostaurin | Midostaurin is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus. Group: Pharmaceutical. CAS No. 120685-11-2. Pack Sizes: 20 mg. Product ID: BBF-05737. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mifepristone Impurities | Mifepristone Impurities, essential components in quality assurance, significantly contribute to evaluating the therapeutic agent Mifepristone, employed in managing Cushing's syndrome and as an abortifacient. These impurities hold crucial importance in maintaining drug purity and efficacy, thereby ensuring its effectiveness in medical treatment applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miglitol Impurities | Miglitol Impurities, integral to the biomedical sector, function as reference benchmarks for quality control in Miglitol production. Serving as a critical antihyperglycemic agent in type 2 diabetes management, the assurance of its purity and efficacy is paramount, underscoring the therapeutic effectiveness essential for such medical interventions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miglustat HCl | Miglustat HCl is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). It also inhibits glucosidase I and II, as well as HIV-1 and HIV-2 infection of peripheral blood mononuclear cells (PBMCs). Group: Pharmaceutical. CAS No. 210110-90-0. Pack Sizes: 10 mg. Product ID: B0084-101894. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miglustat Impurities | Miglustat Impurities constitute a crucial facet in evaluating the purity of Miglustat, a therapeutic agent prescribed for Gaucher's and Niemann-Pick type C diseases. These impurities are instrumental in maintaining the drugs therapeutic potential and safety, scrutinizing structural and compositional deviations from its active pharmaceutical constituents. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milbemycin oxime | Milbemycin oxime is a semi-synthetic macrolide. As a nematocide and insecticide in veterinary medicine, it opens glutamate sensitive chloride channels in neurons of invertebrates that leads to paralysis by hyperpolarisation of these cells and signal transfer blocking. M1-family aminopeptidase: IC50=2.6 μM (Plasmodium falciparum 3D7); Bile acid transporter: IC50=3.6 μM (human); TGR5: IC50=36.4 μM (human); HCT-116: IC50 >50 μM (human); GBM: IC50 >50 μM (human). Uses: A broad spectrum insecticide; used for treatment and prevention of heartworm in dogs and cats. Group: Pharmaceutical. CAS No. 129496-10-2. Pack Sizes: 500 mg. Product ID: BBF-03816. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milbemycin oxime Impurities | Milbemycin oxime impurities function as essential elements in the precise quality assurance and formulation processes of Milbemycin-centric therapeutic solutions. These impurities, pivotal in treating ailments such as heartworm and other parasitic invasions in veterinary sciences, guarantee the safety and efficacy of antiparasitic pharmaceuticals, ensuring steadfast clinical application reliability. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milciclib | Milciclib is an orally bioavailable inhibitor of cyclin-dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activity. CDK2/TRKA inhibitor PHA-848125 AC potently inhibits cyclin-dependent kinase 2 (CDK2) and exhibits activity against other CDKs including CDK1 and CDK4, in addition to TRKA. Inhibition of these kinases may result in cell cycle arrest and apoptosis of tumor cells that express these kinases. CDKs are serine/threonine kinases involved in regulation of the cell cycle and may be overexpressed in some cancer cell types. The neurotrophin receptor TRKA is mutated in a variety of cancer cell types. Group: Pharmaceutical. CAS No. 802539-81-7. Pack Sizes: 5 mg. Product ID: B0084-459709. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mildronate Impurities | Mildronate Impurities, vital constituents within the pharmacological framework, uphold the therapeutic integrity and efficacy of Mildronate in treating ischemic heart ailments and enhancing physical endurance. These impurities function as essential standards in pharmaceutical evaluation, ensuring both safety and therapeutic validity, thereby reinforcing regulatory adherence. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milnacipran-[d5] hydrochloride | Milnacipran-[d5] hydrochloride is a labelled impurity of Milnacipran. Milnaciprana is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat fibromyalgia. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014880. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milnacipran Impurities | Milnacipran Impurities hold vital importance in the pharmaceutical sector, facilitating rigorous quality assurance of Milnacipran, an antidepressant prominently applied in managing major depressive disorder and fibromyalgia. Their analysis assures Milnacipran's safety and effectiveness, ensuring adherence to comprehensive regulatory norms. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milrinone | Milrinone is a phosphodiesterase 3 (PDE3) inhibitor with vasodilator properties, used to increase the heart's contractility. It increases erythrocyte cAMP activity via inhibiting erythrocyte phosphodiesterase. Uses: Increase the heart's contractility. Group: Pharmaceutical. CAS No. 78415-72-2. Pack Sizes: 1 g. Product ID: B0084-291905. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milrinone Impurities | Milrinone Impurities play a crucial role in the biomedical industry as analytical reference standards for the development and validation of assays in cardiac medications. These impurities help ensure the safety and efficacy of milrinone, a drug widely used for managing heart failure by enhancing cardiac output and reducing vascular resistance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miltefosine | Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 58066-85-6. Pack Sizes: 5 g. Product ID: BBF-03908. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miltefosine impurities | Miltefosine impurities, emerging throughout the synthesis process of the antileishmanial and anticancer agent miltefosine, are integral to quality control and analytical scrutiny. Their detection and analysis bolster drug safety and efficacy, particularly against leishmaniasis and select cancer types, enhancing the optimization of pharmaceutical formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Minocycline hydrochloride | Minocycline (INN) is a semi-synthetic broad-spectrum tetracycline antibiotic. Minocycline hydrochloride is the most lipid-soluble form, which binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. In combination with CHIR 99021, (S)-(+)-Dimethindene maleate and human leukemia inhibitory factor, it induces the formation of extended pluripotent stem (EPS) cells. Group: Pharmaceutical. CAS No. 13614-98-7. Pack Sizes: 5 g. Product ID: BBF-03822. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Minocycline Impurities | Minocycline Impurities, integral to the biomedical field, are critical for assessing the purity and safety of minocycline, an antibacterial agent used to treat conditions like acne and bacterial infections. The analysis of these impurities ensures the therapeutic efficacy and regulatory compliance of minocycline formulations in clinical applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Minoxidil Impurities | Minoxidil Impurities are critical in the biomedical industry for quality control in antihypertensive and hair growth treatment formulations. These impurities help ensure the purity and safety profiles of minoxidil products used to treat conditions like androgenetic alopecia and hypertension, thereby safeguarding drug efficacy and consumer safety. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Minoxidil Sulfate | Minoxidil sulfate is the active metabolite of Minoxidil and it is a potent vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener. Group: Pharmaceutical. CAS No. 83701-22-8. Pack Sizes: 100 g. Product ID: B2694-078174. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirabegron | Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Uses: Adrenergic beta-3 receptor agonists. Group: Pharmaceutical. CAS No. 223673-61-8. Pack Sizes: 5 g. Product ID: B0084-182334. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirabegron Impurities | Mirabegron Impurities, serving as quintessential reference standards, fortify the biomedical realm's analytical frameworks, ensuring rigorous quality assessment of Mirabegron—a therapeutic ingeniously devised for overactive bladder management. These impurities are pivotal in validating the safety and therapeutic efficacy of this pharmaceutical agent within clinical applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirabegron impurity 002 | An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Group: Pharmaceutical. CAS No. 81259-56-5. Pack Sizes: 10 mg. Product ID: B2694-338789. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirabegron impurity 003 | An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Group: Pharmaceutical. CAS No. 1018983-85-1. Pack Sizes: 25 mg. Product ID: B2694-338790. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirabegron Impurity 1 ((S)-Mirabegron) | (S)-Mirabegron is an impurity of Mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Group: Pharmaceutical. CAS No. 1796931-48-0. Pack Sizes: 10 mg. Product ID: B1203-473063. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirabegron Impurity 4 | Mirabegron Impurity 4 is an impurity of mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Group: Pharmaceutical. CAS No. 1684452-83-2. Pack Sizes: 25 mg. Product ID: B1370-473061. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirabegron Impurity 8 2HCl | meta-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Group: Pharmaceutical. Pack Sizes: 50 mg. Product ID: B2694-473060. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miraculin (1-20) TFA | Miraculin is a taste improver, which is a glycoprotein extracted from the fruit of Syssepalum dulcificum. Group: Pharmaceutical. Pack Sizes: 100 mg. Product ID: BAT-016123. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miramistin | Miramistin is a topical antiseptic. Group: Pharmaceutical. CAS No. 15809-19-5. Pack Sizes: 5 g. Product ID: BAT-009046. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miriplatin | Miriplatin, a cyclohexane-1,2-diamine platinum(II) dimyristate, is a novel platinum complex that can be used to treat hepatocellular carcinoma (HCC). Group: Pharmaceutical. CAS No. 141977-79-9. Pack Sizes: 250 mg. Product ID: B1370-305452. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miriplatin Impurities | Miriplatin Impurities, paramount in synthesis and analysis, are essential for evaluating the purity of the chemotherapeutic agent Miriplatin, utilized in hepatocellular carcinoma treatment. These impurities facilitate insights into the stability, safety, and side-effect profile, crucial for effective clinical application, thereby underscoring their significant role in oncological pharmacology. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirodenafil Dihydrochloride | Mirodenafil dihydrochloride is a newly developed oral phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. Group: Pharmaceutical. CAS No. 862189-96-6. Pack Sizes: 500 mg. Product ID: B0084-263050. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirodenafil Impurities | Mirodenafil Impurities hold critical importance within the biomedical sector, serving as fundamental elements in quality control and refinement of Mirodenafil, a phosphodiesterase type 5 (PDE5) inhibitor. Employed predominantly in addressing erectile dysfunction, meticulous impurity analysis guarantees therapeutic effectiveness, safety, and adherence to rigorous pharmaceutical criteria. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirogabalin | This active molecular is an α2δ-1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia which related to related to drugs such as gabapentin and pregabalin. Mirogabalin binds to the α2δ calcium channels (1 and 2) and was estimated to be much more potent than pregabalin. In Nov 2015, a Japanese company named Daiichi Sankyo plans a phase III trial for Postherpetic neuralgia and Neuropathic pain (in patients with diabetic peripheral neuropathy and renal impairment) in Japan. In May 2016, Pharmacokinetics and adverse data from a phase I trial in volunteers presented at the 35th Annual Scientific Meeting of the American Pain Society. Uses: Treatment of diabetic peripheral neuropathic pain. Group: Pharmaceutical. CAS No. 1138245-13-2. Pack Sizes: 25 mg. Product ID: B0084-475092. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mirtazapine Impurities | Mirtazapine Impurities, integral to quality control in pharmaceutical sciences, are essential for the meticulous safety evaluation of the antidepressant Mirtazapine. These impurities aid in devising analytical methodologies ensuring drug purity and stability, thereby mitigating adverse reactions and optimizing therapeutic efficacy for major depressive and anxiety disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Miscellaneous | I'm sorry, I cannot provide a description for "Miscellaneous" as it is not a specific product name. Please provide a specific product name for an accurate description. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Misoprostol Impurities | Misoprostol Impurities play an essential role in pharmaceutical quality control and drug development, particularly in ensuring the safety and efficacy of misoprostol formulations. They assist in the analysis of purity and stability, vital for treatments involving gastric ulcers, postpartum hemorrhage prevention, and abortion management. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitiglinide calcium hydrate | Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist. Uses: Hypoglycemic agents. Group: Pharmaceutical. CAS No. 207844-01-7. Pack Sizes: 1 g. Product ID: B0084-474688. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitiglinide Impurities | Mitiglinide Impurities are critical in the pharmaceutical analysis of antidiabetic medications. They are essential for quality control and ensuring pharmacokinetic accuracy in mitiglinide formulations, which are primarily utilized for managing type 2 diabetes by enhancing insulin secretion. These impurities help in monitoring the drug's efficacy and safety during production. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitoguazone dihydrochloride monohydrate | Mitoguazone dihydrochloride monohydrate (CAS# 332360-02-8 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 332360-02-8. Pack Sizes: 100 g. Product ID: B2699-017120. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitomycin C | Mitomycin C is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. And it has an inhibitory effect on tumors. Uses: Mitomycin c is also available as a a 4% mixture in nacl. see "mitomycin c+nacl" sample coa. Group: Pharmaceutical. CAS No. 50-07-7. Pack Sizes: 250 mg. Product ID: BBF-02559. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitomycin Impurities | Mitomycin Impurities are critical in the biomedical field for evaluating and understanding the purity and stability of mitomycin-based chemotherapy drugs. These impurities aid in the detection and quantification of degradation products, ensuring drug safety and effectiveness in treating various cancers, including gastric and pancreatic cancers. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitotane Impurities | Mitotane Impurities stand as an indispensable component within the realm of quality control and pharmacokinetic analysis in oncology, particularly concerning adrenocortical carcinoma management. By revealing metabolic pathways, they enhance Mitotane's safety and efficacy, thereby spearheading transformative therapeutic strategies against this challenging malignancy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitoxantrone | Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. It is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma. Uses: Analgesics. Group: Pharmaceutical. CAS No. 65271-80-9. Pack Sizes: 2.5 g. Product ID: B2693-074515. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitoxantrone Impurities | Mitoxantrone Impurities are critical in the quality control and analysis of Mitoxantrone, a chemotherapeutic agent used to treat certain cancers, including leukemia and breast cancer. Understanding these impurities aids in ensuring drug safety and efficacy, promoting advancements in oncological therapies and pharmaceutical research methodologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mitraphylline | Mitraphylline is an alkaloid isolated from Uncaria rhynchophylla anti-inflammatory activity and inhibiting lipopolysaccharide-mediated activation of primary human neutrophils. Group: Pharmaceutical. CAS No. 509-80-8. Pack Sizes: 5 mg. Product ID: NP0822. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mivebresib | Mivebresib is a BET inhibitor with potential antineoplastic activity. It disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Mivebresib is also a MYC and the TMPRSS2-ETS fusion proteins inhibitor. Mivebresib can inhibit cell growth in susceptible tumors. Uses: Anti-tumor. Group: Pharmaceutical. CAS No. 1445993-26-9. Pack Sizes: 300 mg. Product ID: B0084-475449. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mizagliflozin | Mizagliflozin is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine. It blocks intestinal glucose absorption and reduces GIP secretion in rats and humans, which suggests SGLT1 glucose transport is critical for GIP release. It is used for the treatment of diabetes. Group: Pharmaceutical. CAS No. 666843-10-3. Pack Sizes: 10 mg. Product ID: B2693-476096. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-0731 | MK-0731 is a synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP. Uses: Potential antineoplastic agent. Group: Pharmaceutical. CAS No. 845256-65-7. Pack Sizes: 5 mg. Product ID: B0084-137625. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-1775 | MK-1775, also known as AZD-1775, is a WEE1 inhibitor and a small-molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. Unlike normal cells, most p53-deficient or mutated human cancers lack the G1 checkpoint as p53 is the key regulator of the G1 checkpoint and these cells rely on the G2 checkpoint for DNA repair to damaged cells. Annulment of the G2 checkpoint may therefore make p53-deficient tumor cells more vulnerable to antineoplastic agents and enhance their cytotoxic effect. Group: Pharmaceutical. CAS No. 955365-80-7. Pack Sizes: 300 mg. Product ID: B0084-157422. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-2206 dihydrochloride | MK-2206 is a highly selective Akt inhibitor with IC50 of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. It is undergoing a phase II clinical trial for the treatment of ovarian, fallopian tube, or primary peritoneal cancer where there are mutations in P13K or AKT or low levels of PTEN. Group: Pharmaceutical. CAS No. 1032350-13-2. Pack Sizes: 100 mg. Product ID: B0084-336879. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-4101 | MK-4101 is a potent and selective SMO Inhibitor of the Hedgehog Pathway with anti-tumor activity. MK-4101 targets the Hh pathway in tumor cells, showing the maximum inhibitory effect on Gli1 MK-4101 also induced deregulation of cell cycle and block of DNA replication in tumors. Group: Pharmaceutical. CAS No. 935273-79-3. Pack Sizes: 300 mg. Product ID: B0084-007827. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-4827 (R-enantiomer) | MK-4827 (R-enantiomer) is the R form of MK-4827, which is a PARP inhibitor developed for the treatment of ovarian cancer. Group: Pharmaceutical. CAS No. 1038915-58-0. Pack Sizes: 5 mg. Product ID: B0084-138719. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-4827 tosylate | MK-4827 tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. It has a great activity in cancer cells with mutant BRCA-1 and BRCA-2, >330-fold selective against PARP3, V-PARP and Tank1. Group: Pharmaceutical. CAS No. 1038915-73-9. Pack Sizes: 100 mg. Product ID: B0084-463500. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-5172 | Grazoprevir is a hepatitis C virus protease inhibitor developed for the treatment of hepatitis C. It suppresses NS3 and NS4A, which play a role in the virus splitting its polyprotein into the functional virus proteins. Grazoprevir is often used in combination with elbasvir or ribavirin. Uses: Antiviral agents. Group: Pharmaceutical. CAS No. 1350514-68-9. Pack Sizes: 100 mg. Product ID: B2693-007134. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-8353 | MK-8353 is an orally available ERK1/2 inhibitor. It exhibited antitumor activity in patients with BRAFV600-mutant melanoma. Group: Pharmaceutical. CAS No. 1184173-73-6. Pack Sizes: 50 mg. Product ID: B2693-291615. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-8722 | MK-8722 is a potent pan-AMPK activator that improves glucose homeostasis but induces cardiac hypertrophy. AMPK has long been of interest as a target for the treatment of Type 2 Diabetes Mellitus. Group: Pharmaceutical. CAS No. 1394371-71-1. Pack Sizes: 100 mg. Product ID: B2693-373163. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MKC-3946 | MKC-3946 is a potent inhibitor of inositol-requiring enzyme 1α (IRE1α). It inhibits XBP1 mRNA splicing and exhibits cytotoxicity against AML cells. MKC-3946 leads to modest growth inhibition in MM cells but has no effect on normal mononuclear cells in vitro. Group: Pharmaceutical. CAS No. 1093119-54-0. Pack Sizes: 300 mg. Product ID: B0084-054003. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ML204 | ML204 is a novel and potential TRPC4 Channel inhibitor. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise with an IC(50) value of 0.96 μm and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation. Group: Pharmaceutical. CAS No. 5465-86-1. Pack Sizes: 100 mg. Product ID: B0084-470926. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ML241 | ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the treatment of cancer. Uses: Anticancer. Group: Pharmaceutical. CAS No. 1346528-06-0. Pack Sizes: 100 mg. Product ID: B0084-475332. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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