BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Elacridar | Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Group: Pharmaceutical. CAS No. 143664-11-3. Pack Sizes: 100 mg. Product ID: B0084-311800. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Elacridar hydrochloride | Elacridar is an orally bioavailable inhibitor of P-glycoprotein (P-gp) and ABCG2. Group: Pharmaceutical. CAS No. 143851-98-3. Pack Sizes: 50 mg. Product ID: B0084-458012. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elafibranor | Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Group: Pharmaceutical. CAS No. 923978-27-2. Pack Sizes: 250 mg. Product ID: B0084-074234. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elagolix sodium | Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Uses: Endometriosis; uterine leiomyoma. Group: Pharmaceutical. CAS No. 832720-36-2. Pack Sizes: 25 mg. Product ID: B0084-354739. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elagolix sodium Impurities | Elagolix sodium Impurities, essential in the biomedical domain, ensure the pristine standard and safety of Elagolix, utilized for addressing endometriosis and uterine fibroids. The meticulous identification and regulation of these impurities are crucial for drug efficacy and patient well-being, fostering the development of enhanced therapeutic methodologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elbasvir | Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis C virus and is currently under Phase II trail. Uses: Elbasvir has been found to restrain viral phosphoprotein so that could be used against hepatitis c virus and is currently under phase ii trail. Group: Pharmaceutical. CAS No. 1370468-36-2. Pack Sizes: 100 mg. Product ID: B0084-474522. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eldecalcitol | Eldecalcitol, a vitamin D analog, has strong effects to reduce calcium reabsorption into the body from bones, therefore increasing bone mineral density, and to increase calcium absorption in intestines. Group: Pharmaceutical. CAS No. 104121-92-8. Pack Sizes: 1 mg. Product ID: B0084-305756. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eldecalcitol Intermediate A | Eldecalcitol Intermediate A is an intermediate of eldecalcitol, a vitamin D3 analogue for the treatment of osteoporosis. Eldecalcitol is more active in bone resorption inhibition in comparison with alfacalcidol. Group: Pharmaceutical. CAS No. 200636-54-0. Pack Sizes: 1 mg. Product ID: B1960-112373. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eldecalcitol Intermediate CD | Eldecalcitol Intermediate CD is a vital component used in the compound industry. Specifically designed for pharmaceutical applications, this intermediate plays a crucial role in the synthesis of Eldecalcitol, a drug used for the research of osteoporosand other bone-related disorders. Group: Pharmaceutical. CAS No. 144848-24-8. Pack Sizes: 10 mg. Product ID: B1960-112375. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eleclazine | Eleclazine is a selective Sodium channel antagonist. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart's electrical cycle) in patients with long QT-3 (LQT3) syndrome. Phase III clinical trilas for the treatment of Long QT syndrome, Phase II/III clinical trilas for the treatment of Hypertrophic cardiomyopathy and Phase II clinical trilas for the treatment of Ventricular arrhythmias are on-going. Uses: Long qt syndrome;hypertrophic cardiomyopathy;ventricular arrhythmias. Group: Pharmaceutical. CAS No. 1443211-72-0. Pack Sizes: 50 mg. Product ID: B2693-475446. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elesclomol | Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway. Normal cells are spared because the increase in the level of oxidative stress induced by this agent is below the threshold at which apoptosis is induced. Elesclomol is currently developed by Synta Pharmaceuticals Corp. Group: Pharmaceutical. CAS No. 488832-69-5. Pack Sizes: 25 mg. Product ID: B0084-212109. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eletriptan Impurities | Eletriptan Impurities play a crucial role in the biomedical industry, primarily in quality control and safety testing of eletriptan formulations. Used to identify and characterize potential contaminants, they ensure the efficacy and safety of eletriptan, a drug commonly prescribed for treating migraine headaches. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eleutheroside A | Daucosterol can be used as an efficient and inexpensive neuroprotectant, to which the IGF1-like activity of Daucosterol contributes. Daucosterol could be potentially developed as a medicine for ischemic stroke treatment. Uses: Analgesic. Group: Pharmaceutical. CAS No. 474-58-8. Pack Sizes: 20 mg. Product ID: NP6068. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eleutheroside B1 | Eleutheroside B1 is a coumarin with anti-human influenza virus efficacy. Group: Pharmaceutical. CAS No. 16845-16-2. Pack Sizes: 10 mg. Product ID: B2703-334415. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eleutheroside C | Eleutheroside C is isolated from the root barks of Eleutherococcus senticosus. Group: Pharmaceutical. CAS No. 15486-24-5. Pack Sizes: 5 mg. Product ID: NP4234. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eliglustat hemitartrate | Eliglustat hemitartrate is a specific inhibitor of glucosylceramide synthase. It is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1). It was developed by Genzyme Corp and has been listed by the FDA August 2014. Group: Pharmaceutical. CAS No. 928659-70-5. Pack Sizes: 1 g. Product ID: B2693-474918. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eliprodil | Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia. Uses: Eliprodil is a nr2b-nmda receptor antagonist that was found to have neuroprotective activity in study of ischemia. Group: Pharmaceutical. CAS No. 119431-25-3. Pack Sizes: 50 mg. Product ID: B0084-359860. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ellagic acid | Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. The antiproliferative and antioxidant properties of ellagic acid have prompted research into its potential health benefits. It has been fraudulently marketed as having the ability to prevent and treat a number of human maladies, including cancer, but such claims have not been proven. Ellagic acid can be used in cosmetics material. Uses: Anti-proliferative; anti-oxidant. Group: Pharmaceutical. CAS No. 476-66-4. Pack Sizes: 100 g. Product ID: NP5371. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ELOVL1-IN-2 | ELOVL1-IN-2 is an inhibitor of ELOVL1 (elongation of very-long-chain-fatty acid 1). Group: Pharmaceutical. CAS No. 2761063-79-8. Pack Sizes: 50 mg. Product ID: B1370-149624. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eltoprazine hydrochloride | Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine hydrochloride has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Group: Pharmaceutical. CAS No. 98206-09-8. Pack Sizes: 50 mg. Product ID: B2693-261153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eltrombopag Impurities | Eltrombopag Impurities occupy a crucial role in the refinement and optimization of eltrombopag, an essential therapeutic agent against thrombocytopenia linked to chronic immune thrombocytopenic purpura and hepatitis C. These impurities facilitate rigorous safety and efficacy assessments, ensuring advancement across the pharmaceutical manufacturing spectrum, thereby enhancing therapeutic reliability. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eluxadoline Impurities | Eluxadoline Impurities, integral to the pharmaceutical analysis, are pivotal for evaluating the purity and quality of Eluxadoline, a therapeutic agent for IBS-D. Investigation into these impurities is crucial for enhancing drug formulation techniques, ensuring therapeutic effectiveness, and safeguarding patient health, thereby contributing to superior medicinal efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elvitegravir | Elvitegravir is an HIV-1 integrase strand transfer inhibitor (INSTI) for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Anti-retroviral agents. Group: Pharmaceutical. CAS No. 697761-98-1. Pack Sizes: 50 mg. Product ID: B0084-149112. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Elvitegravir Impurities | Elvitegravir Impurities function as essential components in the quality control realm, ensuring the developmental accuracy of antiretroviral therapies, particularly those addressing HIV. These impurities critically maintain elvitegravir's purity, a pivotal integrase inhibitor, thereby safeguarding the drug's therapeutic effectiveness and patient safety on a global scale. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emamectin Impurities | Emamectin Impurities, integral to biomedical quality assurance, are pivotal in monitoring Emamectin synthesis, a transformative antiparasitic agent. Their presence guarantees the therapeutic reliability and safety of Emamectin formulations, with pronounced significance in veterinary applications targeting ectoparasitic infestations, thus ensuring both efficacy and safety in treatment regimens. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emapunil | Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects. Group: Pharmaceutical. CAS No. 226954-04-7. Pack Sizes: 50 mg. Product ID: B0084-388916. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Embelin | Embelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 uM. Group: Pharmaceutical. CAS No. 550-24-3. Pack Sizes: 100 mg. Product ID: BBF-04074. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| EMD638683 | EMD638683 is a potent SGK1 inhibitor with an IC50 of 3 μM. Group: Pharmaceutical. CAS No. 1181770-72-8. Pack Sizes: 10 mg. Product ID: B2693-457303. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emedastine Impurities | Emedastine Impurities, integral to the pharmaceutical sector, are essential for evaluating the purity and safety of Emedastine, an antihistamine utilized against allergic conjunctivitis. Their role is pivotal in drug formulation studies, ensuring the effectiveness and safety of Emedastine therapeutics, thereby safeguarding patient health through meticulous quality control. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emeramide | Emeramide is a mercury chelator and an antioxidant, for the treatment of mercury poisoning. The molecule consists of two thiol groups and linked via a pair of amide groups. Group: Pharmaceutical. CAS No. 351994-94-0. Pack Sizes: 5 g. Product ID: B0001-470917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emericid | It is produced by the strain of Streptomyces hygroscppicus DS 24 367. It has anti-gram-positive bacterial activity and can be used to treat coccidiosis of poultry. Group: Pharmaceutical. CAS No. 58785-63-0. Pack Sizes: 1 mg. Product ID: BBF-01210. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emodepside | Emodepside, also known as PF 1022-221, a semisynthetic derivative of PF1022A, is efficacious against a variety of gastrointestinal nematodes and used as an anthelmintic drug with broad-spectrum anthelmintic activity. Emodepside is an octapeptide drug that has been approved for use in cats. Group: Pharmaceutical. CAS No. 155030-63-0. Pack Sizes: 1 g. Product ID: BBF-05781. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emodin | Emodin is an anthraquinone found naturally in the roots and barks of numerous plants. It exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways. It has anti-cancer, anti-depressant and anti-microbial effects. Group: Pharmaceutical. CAS No. 518-82-1. Pack Sizes: 50 g. Product ID: BBF-04483. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emodin anthrone | Emodin anthrone is a natural product found in Rhamnus prinoides, Paeonia emodi, and Rumex acetosa with data available. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli. Group: Pharmaceutical. CAS No. 491-60-1. Pack Sizes: 1 g. Product ID: B0001-093033. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emodin Impurities | Emodin Impurities, inherently associated with natural anthraquinone derivatives, are crucial in the realm of pharmacological synthesis and profiling, ensuring medicinal efficacy and safety. Their study in biomedical research illuminates connections to emodin's anticancer, antioxidant, and anti-inflammatory attributes, advancing comprehension of its pharmacokinetic and pharmacodynamic properties. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emopamil | Emopamil is a calcium channel blocker that can be used to prevent renal injury after warm & cold ischemia. Uses: Calcium channel blockers. Group: Pharmaceutical. CAS No. 78370-13-5. Pack Sizes: 100 mg. Product ID: B2693-134176. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin | Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Group: Pharmaceutical. CAS No. 864070-44-0. Pack Sizes: 10 g. Product ID: NP3671. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin α Isomer | Empagliflozin α Isomer is an isomer of empagliflozin, a medication indicated for type 2 diabetes treatment. Group: Pharmaceutical. CAS No. 1620758-33-9. Pack Sizes: 1 mg. Product ID: B0236-003870. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin-[d4] | An isotope labelled of Empagliflozin. Empagliflozin is ued for the treatment of type 2 diabetes in adults. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-013870. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin Destetrahydrofuran Impurity | An impurity of empagliflozin, a medication indicated for type 2 diabetes treatment. Group: Pharmaceutical. CAS No. 864070-37-1. Pack Sizes: 100 mg. Product ID: B0236-470791. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin Impurities | Empagliflozin Impurities are critical in the biomedical industry for quality control in drug manufacturing. These impurities are instrumental in assessing the efficacy and safety of Empagliflozin, a medication primarily used in managing type 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2) to improve glycemic control. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin Impurity 17 | An impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Group: Pharmaceutical. CAS No. 2452301-27-6. Pack Sizes: 10 mg. Product ID: B2694-363124. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin Impurity C | Empagliflozin impurity. Group: Pharmaceutical. CAS No. 864070-43-9. Pack Sizes: 5 mg. Product ID: B0236-470780. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin R-Furanose | Empagliflozin R-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Group: Pharmaceutical. CAS No. 1620758-31-7. Pack Sizes: 10 mg. Product ID: B2694-363123. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin S-Furanose | Empagliflozin S-Furanose is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Group: Pharmaceutical. CAS No. 1620758-32-8. Pack Sizes: 1 mg. Product ID: B2694-363122. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Empagliflozin Tetraacetoxy | Empagliflozin Tetraacetoxy is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Group: Pharmaceutical. CAS No. 1620758-21-5. Pack Sizes: 25 mg. Product ID: B1370-058951. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emraclidine | Emraclidine is a muscarinic M4 receptor positive allosteric modulator. Group: Pharmaceutical. CAS No. 2170722-84-4. Pack Sizes: 25 mg. Product ID: B1370-372977. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emtricitabine | Emtricitabine moderately reduces hepatocyte proliferation independent of effects on mtDNA in HepG2 human hepatoma cells. Group: Pharmaceutical. CAS No. 143491-57-0. Pack Sizes: 10 g. Product ID: NP3265. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Emtricitabine Impurities | Emtricitabine Impurities, found in the biomedical industry, play an essential role in the quality control and analytical characterization of emtricitabine, an antiretroviral drug. This is vital for ensuring drug safety and efficacy in treating HIV infections. The study of these impurities aids in refining drug synthesis and stability profiles. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enalaprilat Dihydrate | Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor. Group: Pharmaceutical. CAS No. 84680-54-6. Pack Sizes: 250 mg. Product ID: B0084-137901. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enalapril EP Impurity D | An impurity of Enalapril. Enalapril is an angiotensin-converting-enzyme inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Group: Pharmaceutical. CAS No. 115729-52-7. Pack Sizes: 500 mg. Product ID: B2694-470980. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enalapril EP Impurity G | An impurity of Enalapril. Enalapril is an angiotensin-converting-enzyme inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Group: Pharmaceutical. CAS No. 460720-14-3. Pack Sizes: 100 mg. Product ID: B2694-470982. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enalapril Impurities | Enalapril Impurities are crucial in the biomedical industry for quality control and assurance of enalapril medications, used primarily in hypertension and heart failure treatment. These impurities help ensure the drug's safety and efficacy by identifying and quantifying unwanted by-products during the medication's synthesis process. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enasidenib | Enasidenib, aslo known as AG-221 and CC-90007, is a potent and selective IDH2 inhibitor with potential anticancer activity (IDH2 = Isocitrate dehydrogenase 2). Group: Pharmaceutical. CAS No. 1446502-11-9. Pack Sizes: 50 mg. Product ID: B0084-470859. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enbucrilate | Enbucrilate is a surgical tissue adhesive. Enbucrilate is under clinical trials for its intervention in gastric variceal bleeding. Group: Pharmaceutical. CAS No. 6606-65-1. Pack Sizes: 5 g. Product ID: B0046-040645. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (E)-N-Caffeoylputrescine | (E)-N-Caffeoylputrescine is a fascinating and intricate natural compound unveiling its potent prowess in studying multifarious afflictions. Harnessing its antioxidant might and unfurling an array of anti-inflammatory attributes, this compound is abundantly residing in the botanical realm, aiding in studying cancer, diabetes and neurodegenerative maladies. Group: Pharmaceutical. CAS No. 29554-26-5. Pack Sizes: 5 mg. Product ID: B0005-053482. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Encorafenib | Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Group: Pharmaceutical. CAS No. 1269440-17-6. Pack Sizes: 150 mg. Product ID: B0084-462563. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| endo-BCN-PNP-carbonate | endo-BCN-O-PNB is a PROTAC linker, which is composed of alkyl chains. endo-BCN-O-PNB can be used to synthesize a range of PROTACs. Group: Pharmaceutical. CAS No. 1263166-91-1. Pack Sizes: 250 mg. Product ID: BP-501259. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Endomorphin 1 | Endomorphin 1 is a high affinity (Ki = 360 pM) and highly selective agonist of theμ-opioid receptor with 4000- and 15000-fold preference over δ and κ respectively and displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Uses: Analgesics, opioid. Group: Pharmaceutical. CAS No. 189388-22-5. Pack Sizes: 50 mg. Product ID: BAT-015992. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Endothelin 1 (swine, human) | Endothelin 1 (swine, human), a vasoconstrictor increased in plasma and explants of patients with uterine leiomyomas, is a synthetic peptide with the sequence of human and swine Endothelin 1 and acts through two types of receptors ETA and ETB. Group: Pharmaceutical. CAS No. 117399-94-7. Pack Sizes: 1 mg. Product ID: BAT-006179. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Endothelin-3, human, mouse, rabbit, rat | Endothelin 3 is a ligand of the endothelin (ET) receptors and a potent vasoconstrictor. Endothelin 3 increases blood pressure in spontaneously hypertensive and normotensive rats, and promotes migration and adhesion of enteric neural crest cells (ENCCs) to the embryonic gut in mice via interaction with ETB. Uses: Vasoconstrictor. Group: Pharmaceutical. CAS No. 117399-93-6. Pack Sizes: 1 mg. Product ID: BAT-006178. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enfuvirtide | Enfuvirtide is a biomimetic peptide of HIV-1 fusion inhibitor with CD4+ cells and it is used to patients with multi-drug resistant HIV. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the HIV-1 virus. Group: Pharmaceutical. CAS No. 159519-65-0. Pack Sizes: 100 mg. Product ID: BAT-010036. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Engeletin | Engeletin is a flavonoid glycoside isolated from the leaves of Engelhardtia roxburghiana Wall. It inhibits a recombinant human aldose reductase. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 572-31-6. Pack Sizes: 100 mg. Product ID: NP1964. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ENMD-2076 | ENMD-2076 is an orally-active, Aurora A/angiogenic kinase inhibitor with a unique kinase selectivity profile and multiple mechanisms of action. ENMD-2076 has been shown to inhibit a distinct profile of angiogenic tyrosine kinase targets in addition to the Aurora A kinase. Aurora kinases are key regulators of mitosis (cell division), and are often over-expressed in human cancers. ENMD-2076 also targets the VEGFR, Flt-3 and FGFR3 kinases which have been shown to play important roles in the pathology of several cancers. ENMD-2076 has shown promising activity in Phase 1 clinical trials in solid tumor cancers, leukemia, and multiple myeloma. ENMD-2076 is currently in a Phase 2 trial for ovarian cancer, and preclinical and clinical activities are ongoing in assessing the compound's applicability for other forms of cancer. Group: Pharmaceutical. CAS No. 934353-76-1. Pack Sizes: 50 mg. Product ID: B2693-156198. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enmein | Enmein is a natural diterpenoid compound found in several plants. Group: Pharmaceutical. CAS No. 3776-39-4. Pack Sizes: 1 mg. Product ID: NP1723. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ENNIATIN B | It is produced by the strain of Fusarium orthoceras var. enniatinum. It has insecticidal and antifungal activity. Uses: Anti-bacterial agents. Group: Pharmaceutical. CAS No. 917-13-5. Pack Sizes: 1 mg. Product ID: BBF-01786. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enniatin B1 | A family of depsipeptide ionophores, produced by several fusarium species. It has antibiotic properties. It is a cytotoxic and insecticidal agent. Group: Pharmaceutical. CAS No. 19914-20-6. Pack Sizes: 1 mg. Product ID: BBF-04590. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enoxaparin sodium | Enoxaparin sodium is an anticoagulant medication used for the prevention of blood clots such as deep vein thrombosis (DVT), and also for the treatment of blood vessel complications in patients with angina and heart attack. Group: Pharmaceutical. CAS No. 679809-58-6. Pack Sizes: 1 g. Product ID: B0046-068182. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enrofloxacin | Enrofloxacin is a fluoroquinolone antibiotic that prevents DNA superhelix and DNA synthesis by inhibiting bacterial DNA gyrase (a type II topoisomerase). It can be used for bacterial diseases caused by sensitive bacteria in livestock and small animals. Group: Pharmaceutical. CAS No. 93106-60-6. Pack Sizes: 100 g. Product ID: BBF-04643. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Enrofloxacin-[d5] | Enrofloxacin-[d5] is the labelled analogue of Enrofloxacin, which is a fluoroquinolone antibiotic. Enrofloxacin is used in the treatment of individual pets and domestic animals. Group: Pharmaceutical. CAS No. 1173021-92-5. Pack Sizes: 10 mg. Product ID: BLP-010799. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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