BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Ceftriaxone EP Impurity E | An impurity of Ceftriaxone, a cephalosporin antibiotic for the treatment of various bacterial infections. Group: Pharmaceutical. CAS No. 58909-56-1. Pack Sizes: 25 mg. Product ID: B2694-468587. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Ceftriaxone Impurities | Ceftriaxone Impurities hold significant importance within pharmaceutical quality control, specifically related to the cephalosporin antibiotic ceftriaxone. By ensuring drug purity and potency, these impurities guarantee therapeutic effectiveness against bacterial pathogens, including pneumonia, bloodstream infections, and meningitis, while maintaining rigorous regulatory compliance in pharmaceutical production. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ceftriaxone sodium hydrate (2:4:7) | Ceftriaxone sodium hydrate is a third-generation cephalosporin antibiotic. Group: Pharmaceutical. CAS No. 104376-79-6. Pack Sizes: 5 g. Product ID: BBF-04629. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cefuroxime Axetil Impurity E | (α Z)-α -(Methoxyimino)-N-[(5aR, 6R)-1, 4, 5a, 6-tetrahydro-1, 7-dioxo-3H, 7H-azeto[2, 1-b]furo[3, 4-d][1, 3]thiazin-6-yl]-2-furanacetamide is an impurity of Cefuroxime Axetil, the 1-(acetyloxy) ethyl ester of Cefuroxime , an injectable second generation cephalosporin with an excellent antibacterial activity. Group: Pharmaceutical. CAS No. 947723-87-7. Pack Sizes: 100 mg. Product ID: B2694-468596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cefuroxime Impurities | Cefuroxime Impurities represent an integral facet in the analytical scrutiny and quality assurance of cefuroxime, a cephalosporin antibiotic vital for combating bacterial afflictions such as respiratory and urinary tract infections, alongside Lyme disease. Vigilant surveillance of these impurities underpins the clinical safety and therapeutic efficacy of cefuroxime formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celastrol | Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice. Group: Pharmaceutical. CAS No. 34157-83-0. Pack Sizes: 10 mg. Product ID: BBF-05811. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib | Celecoxib is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. Uses: Cyclooxygenase 2 inhibitors. Group: Pharmaceutical. CAS No. 169590-42-5. Pack Sizes: 5 g. Product ID: B0084-451901. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib EP Impurity A | A meta positional isomer of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Pharmaceutical. CAS No. 170570-01-1. Pack Sizes: 100 mg. Product ID: B2694-468619. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib EP Impurity B | An isomeric impurity of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Pharmaceutical. CAS No. 331943-04-5. Pack Sizes: 100 mg. Product ID: B2694-468620. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib Impurities | Celecoxib Impurities, derived during the synthesis of celecoxib, are crucial for evaluating drug purity and safety. Studying these impurities enables a deeper understanding of celecoxib's efficacy in treating inflammatory disorders such as arthritis and pain management, ensuring therapeutic consistency and compliance with regulatory standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celecoxib Impurity 2 | An impurity of celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. CAS No. 948293-46-7. Pack Sizes: 10 mg. Product ID: B2694-468624. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celiprolol Impurities | Celiprolol Impurities, essential to the realms of quality control and scientific inquiry, stand as critical elements in the developmental pathway of celiprolol, a beta-adrenergic antagonist employed in hypertension and cardiovascular anomalies. Their role aids in elucidating drug stability, thus ensuring the refinement and effectiveness of therapeutic cardiovascular interventions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celiprolol Impurity B | N,N'-Bis[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-urea is an impurity of Celiprolol which is a cardioselective β1-adrenergic blocker. Group: Pharmaceutical. CAS No. 125579-40-0. Pack Sizes: 10 mg. Product ID: B0573-468635. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cellulose sulfate sodium salt | Cellulose sulfate sodium salt is a critically significant compound within the realm of biomedical sciences, standing as an avant-garde solution catering to the research of paramount viral afflictions such as HIV/AIDS and various sexually transmitted diseases. Group: Pharmaceutical. CAS No. 9005-22-5. Pack Sizes: 10 g. Product ID: B1999-204538. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Celosin H | Celosin H could be used as chemical markers for the quality control of C. argentea seeds. Group: Pharmaceutical. CAS No. 1623405-28-6. Pack Sizes: 25 mg. Product ID: B1370-334693. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cenicriviroc | Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Uses: Ccr2 receptor antagonists; ccr5 receptor antagonists. Group: Pharmaceutical. CAS No. 497223-25-3. Pack Sizes: 50 mg. Product ID: B2693-454394. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cenicriviroc Impurities | Cenicriviroc Impurities are crucial within the biomedical field for ensuring the purity and efficacy of Cenicriviroc, a chemokine receptor antagonist used to treat HIV infection. Their analysis provides insights into drug stability and safety, supporting the development of effective treatment regimens against HIV. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cenicriviroc mesylate | Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Group: Pharmaceutical. CAS No. 497223-28-6. Pack Sizes: 100 mg. Product ID: B0084-286545. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cephalexin Impurities | Cephalexin Impurities are critical in the pharmaceutical industry for assessing the purity and stability of the antibiotic cephalexin. They aid in identifying and quantifying degradation products, ensuring drug safety, efficacy, and compliance with regulatory standards. These impurities are vital for quality control in the development of cephalexin-based treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cephalocyclidin A | Cephalocyclidin A is isolated from the fruits of Cephalotaxus harringtonia var. nana. Group: Pharmaceutical. CAS No. 421583-14-4. Pack Sizes: 1 mg. Product ID: NP0402. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cephalomannine Impurities | Cephalomannine Impurities, notable in the biomedical sector, are crucial for quality control and development of antineoplastic agents like Taxol. These impurities serve as reference standards in the synthesis of drugs targeting ovarian and breast cancer, aiding in the enhancement of therapeutic efficacy and safety in oncology treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cephalosporin C sodium salt | Cephalosporin C sodium salt is the salt form of cephalosporin C, which is an antibiotic isolated from fungi of the genus Acremonium. Group: Pharmaceutical. CAS No. 51762-04-0. Pack Sizes: 1 g. Product ID: BBF-04162. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cephalosporin C Zinc Salt | Cephalosporin C zinc salt is the salt form of cephalosporin C, which is an antibiotic isolated from fungi of the genus Acremonium. Cephalosporin C has weak resistance to gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Group: Pharmaceutical. CAS No. 59143-60-1. Pack Sizes: 1 g. Product ID: BBF-03774. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cepharanthine | Cepharanthine (CEP) is a biscoclaurine alkaloid isolated from Stephania cepharantha. It has anticancer, antiinflammatory, antiallergic, immunomo- dulatory, and many other interesting biological activities. Cepharanthine has been widely used in Japan for more than 40 years to treat a wide variety of acute and chronic diseases. CEP inhibits tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppresses cytokine production. It has also been shown to scavenge free radicals and to have a protective effect against some of the responses mediated by pro-inflammatory cytokines such as TNF-α, interleukin (IL)-1β and IL6. CEP has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. Uses: Anti-tumor/anti-inflammatory. Group: Pharmaceutical. CAS No. 481-49-2. Pack Sizes: 10 g. Product ID: NP0541. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cephradine | It is produced by the strain of Semisynthetic first generation cephalosporin. It has the commonness of the first generation cephalosporin and its antibacterial action is similar to that of cefalexin. It is characterized by that it can be injected or given orally. Uses: A first generation cephalosporin antibiotic. Group: Pharmaceutical. CAS No. 38821-53-3. Pack Sizes: 50 g. Product ID: BBF-00762. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cerdulatinib HCl | Cerdulatinib is a dual SYK/JAK inhibitor. It significantly reduces cell viability in a subset of NHL cell lines, and induces apoptosis in BCR-signaling competent NHL cell lines. Group: Pharmaceutical. CAS No. 1369761-01-2. Pack Sizes: 10 mg. Product ID: B0084-463402. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ceritinib | An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 1032900-25-6. Pack Sizes: 250 mg. Product ID: B0084-462148. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cerivastatin Impurities | Cerivastatin Impurities are critical reference standards used in the analytical testing and quality control of the cholesterol-lowering drug, cerivastatin. These impurities help ensure the drug's potency and safety by identifying and quantifying any unwanted by-products, thus playing a crucial role in maintaining pharmaceutical quality standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ceruletide | Caerulein, a CCK agonist, could be used in paralytic ileus and diagnostic aid in pancreatic malfunction. Group: Pharmaceutical. CAS No. 17650-98-5. Pack Sizes: 10 mg. Product ID: BAT-010764. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetilistat Impurities | Cetilistat Impurities are utilized in the biomedical industry to identify and quantify trace levels of impurities in cetilistat, an anti-obesity drug. These impurities are crucial for ensuring the drug's safety, efficacy, and quality in the treatment of obesity-related diseases, facilitating enhanced pharmaceutical formulations and regulatory compliance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetirizine EP Impurity B Dihydrochloride | Cetirizine EP Impurity B Dihydrochloride is an impurity of Cetirizine, a second-generation antihistamine used to treat allergic rhinitis, dermatitis, and urticaria. Group: Pharmaceutical. CAS No. 1000690-91-4. Pack Sizes: 100 mg. Product ID: B2694-064738. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetirizine EP Impurity D | An impurity of Cetirizine, an antihistamine used to relieve allergy symptoms. Group: Pharmaceutical. CAS No. 346451-15-8. Pack Sizes: 100 mg. Product ID: B2694-468711. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetirizine Glycerol Ester Impurity | An impurity of cetirizine, an antihistamine used to relieve allergy symptoms. Group: Pharmaceutical. CAS No. 1243652-36-9. Pack Sizes: 10 mg. Product ID: B2694-468713. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetirizine Impurities | Cetirizine Impurities are crucial in the quality control and development of antihistamine drugs, particularly cetirizine, used to treat allergic conditions like hay fever and urticaria. Their characterization ensures drug purity and safety, facilitating the improvement and synthesis of effective allergy medications in the pharmaceutical industry. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetirizine methyl ester dihydrochloride | Cetirizine methyl ester dihydrochloride is a derivative of cetirizine, an antihistamine drug for the relief of symptoms of allergy and cold like sneezing and itching. Group: Pharmaceutical. CAS No. 83881-48-5. Pack Sizes: 50 mg. Product ID: B0212-000346. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetirizine N-Oxide Sodium Salt | An impurity of Cetirizine, which is an antihistamine used to relieve allergy symptoms. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-449746. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetrorelix | Cetrorelix is a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Uses: Fertility agents. Group: Pharmaceutical. CAS No. 120287-85-6. Pack Sizes: 25 mg. Product ID: BAT-015281. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetrorelix diacetate | Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist. Under the trade name Cetrotide, It is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. Group: Pharmaceutical. CAS No. 130143-01-0. Pack Sizes: 50 mg. Product ID: BAT-010074. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetrorelix Impurities | Cetrorelix Impurities hold vital significance in the assessment of purity and pharmacokinetic profiles of Cetrorelix, a GnRH antagonist pivotal for hormone-sensitive treatments such as prostate cancer and infertility. The exploration of these impurities enhances formulation refinement, ensuring therapeutic safety and efficacy, thus advancing pharmaceutical efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cevimeline Impurities | Cevimeline Impurities, indispensable in pharmaceutical refinement, serve a critical function in the formulation of cevimeline for Sjögren's syndrome's xerostomia relief. Their presence is crucial for delineating safety frameworks, enhancing the understanding and elevation of cevimeline's therapeutic efficacy and quality benchmarks. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CF-101 | CF101 is a specific agonist to the A3 adenosine receptor, which inhibits the development of colon carcinoma growth in cell cultures and xenograft murine models. CF101 has been shown to downregulate PKB/Akt and NF-κB protein expression level. CF101 potentiates the cytotoxic effect of 5-FU, thus preventing drug resistance. The myeloprotective effect of CF101 suggests its development as an add-on treatment to 5-FU. Group: Pharmaceutical. CAS No. 152918-18-8. Pack Sizes: 50 mg. Product ID: B2693-256549. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Group: Pharmaceutical. CAS No. 910232-84-7. Pack Sizes: 100 mg. Product ID: B0084-430556. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CGM097 | CGM097 is an orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, p53/HDM2 interaction inhibitor CGM097 inhibits the binding of the HDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53. By preventing this HDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited, which may result in the restoration of p53 signaling and, thus, the p53-mediated induction of tumor cell apoptosis. HDM2, a zinc finger nuclear phosphoprotein, is a negative regulator of the p53 pathway, often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Group: Pharmaceutical. CAS No. 1313363-54-0. Pack Sizes: 5 mg. Product ID: B0084-462483. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CGP 35348 | CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynaptic than presynaptic receptors. Group: Pharmaceutical. CAS No. 123690-79-9. Pack Sizes: 25 mg. Product ID: B1370-360418. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CGP 52432 | CGP52432 is a potent and selective GABAB receptor antagonist with IC50 value of 85 nM. Group: Pharmaceutical. CAS No. 139667-74-6. Pack Sizes: 20 mg. Product ID: B0084-211080. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CGS 15943 | CGS 15943 is a potent and orally bioactive adenosine receptor antagonist (Ki = 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors, respectively). Group: Pharmaceutical. CAS No. 104615-18-1. Pack Sizes: 100 mg. Product ID: B2693-159610. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CH5424802 Hydrochloride | CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Group: Pharmaceutical. CAS No. 1256589-74-8. Pack Sizes: 1 g. Product ID: B0084-463153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chalepensin | Chalepensin is a furanocoumarin found in several medicinal Rutaceae plants. Chalepensin acts as a cytochrome P450 (P450, CYP) inhibitor that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepensin also exhibits an antimicrobial effect against Streptococcus mutans. Group: Pharmaceutical. CAS No. 13164-03-9. Pack Sizes: 5 mg. Product ID: NP1084. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chalkone Impurities | Chalkone Impurities, known for their diverse chemical properties, play a pivotal role in the pharmaceutical industry by aiding in the synthesis of anticancer and anti-inflammatory drugs. These impurities are instrumental in understanding drug stability and efficacy, thereby facilitating advancements in therapeutic strategies for diseases like cancer and arthritis. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chamaechromone | Chamaechromone is isolated from the roots of Stellera chamaeja sme. Chamaechromone can undergo extensive phase I and phase II metabolism in rat. Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α-naphthoflavone, and predominantly catalyzed by recombinant human cytochrome P450 1A2. Group: Pharmaceutical. CAS No. 93413-00-4. Pack Sizes: 5 mg. Product ID: NP2301. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chamigrenal | Chamigrenal, a pharmacological treatment of anxiety disorders, intricately works towards ameliorating the perturbed functioning of the GABA receptors that ensue due to the hyperactivity of the brain. The convoluted mechanism of action mediates a stupor gently and minimizes the manifestation of anxiety symptoms. Additionally, it occasionally serves as an adjuvant in the management of insomnia. Group: Pharmaceutical. CAS No. 19912-84-6. Pack Sizes: 5 mg. Product ID: B0005-465632. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chaparrinone | Chaparrinone is a triterpenoid found in Quassia undulata and Samadera bidwillii. Chaparrinone has antimalarial and cytotoxic activities against Plasmodium falciparum and P-388 cells (IC50: 0.037 and 0.34 μg/mL respectively). Group: Pharmaceutical. CAS No. 22611-34-3. Pack Sizes: 5 mg. Product ID: B1370-061698. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CHAPS | CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. It is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. It is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. Uses: Used as a non-denaturing biological detergent; chaps is a zwitterionic detergent used in the laboratory to solubilize biological macromolecules such as proteins. it is used as a non-denaturing solvent in the process of protein purification and is especially useful in purifying membrane proteins, which are often sparingly soluble or insoluble in aqueous solution due to their native hydrophobicity. Group: Pharmaceutical. CAS No. 75621-03-3. Pack Sizes: 50 g. Product ID: B1370-300063. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Charybdotoxin | Charybdotoxin is a Ca2+-activated K+ channel blocker used as an ADC Cytotoxin. Group: Pharmaceutical. CAS No. 95751-30-7. Pack Sizes: 0.5 mg. Product ID: BAT-006184. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chebulic acid | Chebulic acid is a phenol isolated from Terminalia chebula with potent anti-oxidant activity. Group: Pharmaceutical. CAS No. 23725-05-5. Pack Sizes: 10 mg. Product ID: NP4635. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cheilanthifoline | Cheilanthifoline is an alkaloid isolated from rhizomes of Sinomenium acutum with anti-osteoclastogenic property. Group: Pharmaceutical. CAS No. 483-44-3. Pack Sizes: 5 mg. Product ID: B0005-053767. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chelerythrine | Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable protein kinase C inhibitor. It is also the major active natural product found in the plant Zanthoxylum clava-herculis, exhibiting anti-bacterial activity against Staphylococcus aureus. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy. Uses: Antibacterial agent. Group: Pharmaceutical. CAS No. 34316-15-9. Pack Sizes: 50 mg. Product ID: NP0509. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chelerythrine chloride | Chelerythrine is a cell-permeable inhibitor of protein kinase C (IC50 = 660 nM) with a wide range of biological activities. Group: Pharmaceutical. CAS No. 3895-92-9. Pack Sizes: 50 mg. Product ID: BBF-04087. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (-)-Chelidonine | (-)-Chelidonine is an alkaloid isolated from Glaucium squamigerum. Group: Pharmaceutical. CAS No. 88200-01-5. Pack Sizes: 1 mg. Product ID: NP0676. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CHEMS | CHEMS is an acidic cholesterol ester. It self-assembles into bilayers in alkaline and neutral aqueous media. Group: Pharmaceutical. CAS No. 1510-21-0. Pack Sizes: 10 g. Product ID: B4059-084617. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chicanin | Chicanin is a lignan isolated from the fruits of Osmanthus fragrans. Studies show that chicanine exhibits anti-inflammatory activity on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways and anti-proliferative effect on prostate cells. Group: Pharmaceutical. CAS No. 78919-28-5. Pack Sizes: 5 mg. Product ID: B0005-053763. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chilenine | Chilenine is an alkaloid isolated from the leaves of Hydrastis canadensis L. Group: Pharmaceutical. CAS No. 71700-15-7. Pack Sizes: 1 mg. Product ID: NP0746. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chimmitecan | Chimmitecan is a potent topoisomerase I inhibitor. Chimmitecan is also an active metabolite of simmitecan. Chimmitecan displays outstanding activity in vitro and in vivo. The substitution at the 9-position benefits chimmitecan a salient anti-MDR activity, stability in human serum albumin, improved solubility, and oral availability, which might favorably promise its therapeutic potential in clinical settings. Group: Pharmaceutical. CAS No. 185425-25-6. Pack Sizes: 5 mg. Product ID: BADC-01397. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chimonanthine | Chimonanthine is an alkaloid isolated from the flower buds of Chimonanthus praecox. Group: Pharmaceutical. CAS No. 5545-89-1. Pack Sizes: 5 mg. Product ID: B0005-053747. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CHIR-090 | CHIR-090 is a very potent and tight-binding inhibitor of LpxC, which is a zinc-dependent amidase and present in almost all Gram-negative bacteria, and is a promising target for the development of novel antibiotic substances against multigrug-resistant Gram-negative bacteria. Its Ki value is 4.0 nM. It displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. It has a different selectivity with the reported LpxC inhibitor L-161. It has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli by inhibiting LpxC orthologs at low nM concentrations. It is an excellent lead for the further development of new antibiotics targeting the lipid A pathway. Uses: Chir-090 displays two-step time-dependent inhibition and kills a wide range of gram-negative pathogens as effectively as ciprofloxacin or tobramycin. it has excellent antibiotic activity against pseudomonas aeruginosa and escherichia coli by inhibiting lpxc orthologs at low nm concentrations. Group: Pharmaceutical. CAS No. 728865-23-4. Pack Sizes: 300 mg. Product ID: B0084-474822. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CHIR-99021 | CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES). Uses: Potential antineoplastic agent. Group: Pharmaceutical. CAS No. 252917-06-9. Pack Sizes: 100 mg. Product ID: B0084-462893. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 9012-76-4. Pack Sizes: 1kg. Product ID: B1370-187887. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chlomethoxyfen-[d3] | Chlomethoxyfen-[d3] is a deuterium labelled Chlomethoxyfen, a larely obsolete herbicide. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014107. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chlorambucil | Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. Group: Pharmaceutical. CAS No. 305-03-3. Pack Sizes: 5 g. Product ID: B1370-065622. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chlorambucil Impurities | Chlorambucil Impurities, present during the synthesis of the chemotherapeutic agent Chlorambucil, are pivotal in ensuring drug purity and efficacy for treating chronic lymphocytic leukemia and Hodgkin's lymphoma. Monitoring and quantifying these impurities are crucial for enhancing the safety and effectiveness of this widely utilized cancer treatment. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
Would you like to list your products on UK Chemical Suppliers?
Our database is helping our users find suppliers everyday.