BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| a2-Macroglobulin (human proteinmoiety reduced) (9CI) | a2-Macroglobulin (human proteinmoiety reduced) (9CI). Group: Pharmaceutical. Alternative Names: A2M; A-2-M, HUMAN; ALPHA2M; ALPHA2-MACROGLOBIN, HUMAN; ALPHA2-MACROGLOBULIN; ALPHA2-MACROGLOBULIN, HUMAN; ALPHA2-MACROGLOBULIN, HUMAN PLASMA; ALPHA-2 MACROGLOBULIN PLASMA. CAS No. 95568-41-5. Pack Sizes: 1mg;1g;10g. Product ID: 95568-41-5. Custom synthesis is available. Send your inquiries for more information. |  London |
| A2 N-Glycan | A2 N-Glycan is an indispensable biocompatible and bioactive glycobiology compound, aiding in the meticulous analysand comprehensive characterization of glycoproteins. Group: Pharmaceutical. Alternative Names: Disialo (2,6), biantennary (A2); A2 glycan; A2G2S2 N-glycan; Di-sialylated, galactosylated, bi-antennary N-linked glycan Mannotriose-di-(N-acetyl-D-glucosamine), bis([N-acetyl-D-neuraminyl]-galactosyl-[N-acetyl-D-glucosaminyl]). CAS No. 71496-55-4. Pack Sizes: 1mg;1g;10g. Product ID: 71496-55-4. Molecular formula: C84H138N6O62. Mole weight: 2224. Custom synthesis is available. Send your inquiries for more information. | London |
| A2-PE | A2-PE. Uses: A pigment that forms as a byproduct of the visual cycle in vertebrates, which accumulates in retinal pigment epithelial cells over time leading to decline in cellular function. Group: Pharmaceutical. Alternative Names: 2-[(1E,3E,5E,7E)-2,6-Dimethyl-8-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3,5,7-octatetraen-1-yl]-1-[4-hydroxy-4-oxido-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-4-[(1E,3E,5E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3,5-hexatrien-1-yl]pyridinium; DP-A2-PE. CAS No. 863180-05-6. Pack Sizes: 1mg;1g;10g. Product ID: 863180-05-6. Molecular formula: C77H125NO8P. Mole weight: 1223.79. Custom synthesis is available. Send your inquiries for more information. | London |
| A2ti-1 | A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. Group: Pharmaceutical. Alternative Names: Acetamide, 2-[[4-(2-ethylphenyl)-5-[(2-methylphenoxy)methyl]-4H-1,2,4-triazol-3-yl]thio]-; 2-({4-(2-Ethylphenyl)-5-[(2-methylphenoxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide. CAS No. 570390-00-0. Pack Sizes: 10 mg. Product ID: B1370-060255. Molecular formula: C20H22N4O2S. Mole weight: 382.48. Custom synthesis is available. Send your inquiries for more information. | London |
| A2ti-2 | A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 230 μM. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. Group: Pharmaceutical. Alternative Names: 2-{5-[(2-methylphenoxy)methyl]-4-phenyl-1,2,4-triazol-3-ylthio}acetamide; Acetamide, 2-[[5-[(2-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl]thio]-; 2-({5-[(2-Methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide. CAS No. 482646-13-9. Pack Sizes: 100 mg. Product ID: B1370-382474. Molecular formula: C18H18N4O2S. Mole weight: 354.43. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317491 | A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Group: Pharmaceutical. Alternative Names: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. CAS No. 475205-49-3. Pack Sizes: 1mg;1g;10g. Product ID: 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317491 sodium salt hydrate | A-317491 sodium salt hydrate is a potent, selective antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. It reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Molecular formula: C33H29NNaO9. Mole weight: 606.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317567 | Acid Sensing Ion Channels (ASICs) are a group of sodium-selective ion channels that are activated by low extracellular pH. A-317567 is a novel non-amiloride blocker. Group: Pharmaceutical. Alternative Names: A317567; 6-{2-[2-methyl-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]cyclopropyl}naphthalene-2-carboximidamide. CAS No. 371217-32-2. Pack Sizes: 1mg;1g;10g. Product ID: 371217-32-2. Molecular formula: C27H31N3. Mole weight: 397.56. Custom synthesis is available. Send your inquiries for more information. | London |
| A 33 | A 33 is a potent and selective PDE4B inhibitor (IC50 = 15 nM) that exhibits >100-fold selectivity for PDE4B over 4D. Group: Pharmaceutical. Alternative Names: 2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid. CAS No. 915082-52-9. Pack Sizes: 1mg;1g;10g. Product ID: 915082-52-9. Molecular formula: C19H18ClN3O2S. Mole weight: 387.88. Custom synthesis is available. Send your inquiries for more information. | London |
| A 331440 dihydrochloride | A 331440 dihydrochloride is a histamine H3 receptor antagonist (Ki = 21.7 and 22.7 nM for rat and human H3 receptors, respectively). A 331440 reduces weight in a diet-induced obesity model. Group: Pharmaceutical. Alternative Names: A-331440 dihydrochloride; A 331440 dihydrochloride; A331440 dihydrochloride; 4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride. CAS No. 1049740-32-0. Pack Sizes: 1mg;1g;10g. Product ID: 1049740-32-0. Molecular formula: C22H27N3O.2HCl. Mole weight: 422.39. Custom synthesis is available. Send your inquiries for more information. | London |
| A-331440 DIHYDROCHLORIDE | A-331440 DIHYDROCHLORIDE. Group: Pharmaceutical. CAS No. 392338-13-5. Pack Sizes: 1mg;1g;10g. Product ID: 392338-13-5. Molecular formula: C22H27N3O ??· 2HCl. Mole weight: 422.39. Custom synthesis is available. Send your inquiries for more information. | London |
| A 350619 | A 350619 is an activator of soluble guanylyl cyclase (sGC) that stimulates basal sGC and synergistically activates sGC in the presence of NO. It is effective for the use of ED treatment. Group: Pharmaceutical. Alternative Names: A-350619; A350619; 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide. CAS No. 538368-27-3. Pack Sizes: 1mg;1g;10g. Product ID: 538368-27-3. Molecular formula: C21H25ClN2OS. Mole weight: 389. Custom synthesis is available. Send your inquiries for more information. | London |
| A 350619 hydrochloride | A 350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC) that stimulates basal sGC and synergistically activates sGC in the presence of NO. It is effective for the use of ED treatment. Uses: The treatment of ed. Group: Pharmaceutical. Alternative Names: A-350619 hydrochloride; A350619 hydrochloride; A 350619 hydrochloride; 3-[2-[(4-Chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride. CAS No. 1217201-17-6. Pack Sizes: 1mg;1g;10g. Product ID: 1217201-17-6. Molecular formula: C21H25ClN2OS.HCl. Mole weight: 425.41. Custom synthesis is available. Send your inquiries for more information. | London |
| A 357300 hydrochloride | A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derived neuroblastoma s.c. xenograft growth rate with a treatment-to-control (T/C) ratio at day 24 of 0.19 (P < 0.001) without toxicity. Uses: Novel treatment of neuroblastoma. Group: Pharmaceutical. Alternative Names: A-357300; A 357300; A357300; N'-(3-amino-2-hydroxy-5-(isopropylthio)pentanoyl)-3-chlorobenzohydrazide hydrochloride. CAS No. 369358-07-6. Pack Sizes: 1mg;1g;10g. Product ID: 369358-07-6. Molecular formula: C15H22ClN3O3S.HCl. Mole weight: 396.33. Custom synthesis is available. Send your inquiries for more information. | London |
| A-366 | A-366 is a peptide-competitive inhibitor of the G9a/GLP histone lysine methyltransferase (IC50 = 3.3 nM) and is approximately 1000-fold selective over other methyltransferases. Group: Pharmaceutical. Alternative Names: A 366; A366. CAS No. 1527503-11-2. Pack Sizes: 100 mg. Product ID: B2693-474604. Molecular formula: C19H27N3O2. Mole weight: 329.44. Custom synthesis is available. Send your inquiries for more information. | London |
| A-366833 | A-366833 is a an agonist at neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Uses: Neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Group: Pharmaceutical. Alternative Names: A-366833; A 366833; A366833; 5-[(1R,5S)-3,6-diazabicyclo[3.2.0]heptan-6-yl]pyridine-3-carbonitrile. CAS No. 370882-41-0. Pack Sizes: 1mg;1g;10g. Product ID: 370882-41-0. Molecular formula: C11H12N4. Mole weight: 200.24. Custom synthesis is available. Send your inquiries for more information. | London |
| A37 | A37 is an aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC50 = 4.6 μM; Ki = 300 nM). It competitively binds to the aldehyde binding pocket of ALDH1A1, resulting in the disruption of spheroid formation and a decrease of cell viability in ovarian cancer cells in vitro. Group: Pharmaceutical. Alternative Names: Ethyl 2-[[3,4-dihydro-4-oxo-3-[3-(1-pyrrolidinyl)propyl][1]benzothieno[3,2-d]pyrimidin-2-yl]thio]acetate; CM037; CM-037; CM 037; A37; A-37; A 37. CAS No. 896795-60-1. Pack Sizes: 1mg;1g;10g. Product ID: 896795-60-1. Molecular formula: C21H25N3O3S2. Mole weight: 431.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A-381393 | A-381393 is a potent and selective dopamine D4 receptor agonist. Group: Pharmaceutical. Alternative Names: A 381393; CHEMBL127257. CAS No. 726174-00-1. Pack Sizes: 1mg;1g;10g. Product ID: 726174-00-1. Molecular formula: 20H24N4. Mole weight: 320.4. Custom synthesis is available. Send your inquiries for more information. | London |
| A-395 | A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions, and can effectively inhibit the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM. Group: Pharmaceutical. Alternative Names: 3-Pyrrolidinamine, 1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-[4-[4-(methylsulfonyl)-1-piperazinyl]phenyl]-, (3R,4S)-; (3R,4S)-1-(7-Fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-{4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-3-pyrrolidinamine. CAS No. 2089148-72-9. Pack Sizes: 1mg;1g;10g. Product ID: 2089148-72-9. Molecular formula: C26H35FN4O2S. Mole weight: 486.65. Custom synthesis is available. Send your inquiries for more information. | London |
| A-(3-aminobenyl)butyric acid hydrochloride | A-(3-aminobenyl)butyric acid hydrochloride. Group: Pharmaceutical. CAS No. 16623-25-9. Pack Sizes: 1mg;1g;10g. Product ID: 16623-25-9. Molecular formula: C11H15NO2. Mole weight: 193.24. Custom synthesis is available. Send your inquiries for more information. | London |
| A3 Glycan, 2-AA labelled | A3 Glycan, 2-AA labelled, a critical and indispensable instrument in the biomedical sector, is utilized for exploring glycan expression in diverse illnesses, notably cancer and autoimmune disorders. It acts as the ideal substance for glycan analysis and characterization by advanced technologies like mass spectrometry and chromatography. Furthermore, A3 Glycan, 2-AA labelled is crucial for triggering glycomics-related biomarker discovery scientific investigations ensuing precision medication breakthroughs. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Custom synthesis is available. Send your inquiries for more information. | London |
| A3 Glycan, 2-AB labelled | A3 Glycan, 2-AB labelled. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Custom synthesis is available. Send your inquiries for more information. | London |
| A-3 HYDROCHLORIDE | A-3 HYDROCHLORIDE. Group: Pharmaceutical. Alternative Names: A-3 HYDROCHLORIDE; A-3; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE; N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONA. CAS No. 78957-85-4. Pack Sizes: 1mg;1g;10g. Product ID: 78957-85-4. Molecular formula: C12H14Cl2N2O2S. Mole weight: 321.22. Custom synthesis is available. Send your inquiries for more information. | London |
| A3 N-Glycan | A3 N-Glycan is a vital biomolecule commonly found on the surface of many cells. It plays a crucial role in various biological processes, such as cell signaling, immune response, and disease progression. This particular N-glycan is extensively studied in the biomedical industry due to its involvement in numerous diseases, including cancer, autoimmune disorders, and infectious diseases. Group: Pharmaceutical. Alternative Names: Trisialylated, galactosylated, triantennary (A3); A3 glycan; A3G3S3 Glycan; (NeuNAc-Gal-GlcNAc)3Man3(GlcNAc)2; Tri-sialylated, galactosylated, tri-antennary N-linked glycan; Mannotriose-di-(N-acetyl-D-glucosamine), tris(sialyl-galactosyl-N-acetyl-D-glucosaminyl; D-Glucose, O-(N-acetyl-α-neuraminosyl)-[2→3(or 2→6)]-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-O-[O. CAS No. 145164-24-5. Pack Sizes: 1mg;1g;10g. Product ID: 145164-24-5. Molecular formula: C109H178N8O80. Mole weight: 2880.59. Custom synthesis is available. Send your inquiries for more information. | London |
| A3(or5)-[[4-[ethyl[2-(trimethylammonio)ethyl]amino]phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium dimethyl disulfate | A3(or5)-[[4-[ethyl[2-(trimethylammonio)ethyl]amino]phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium dimethyl disulfate. Group: Pharmaceutical. CAS No. 97861-86-4. Pack Sizes: 1mg;1g;10g. Product ID: 97861-86-4. Molecular formula: C17H29N7.2CH3O4S. Custom synthesis is available. Send your inquiries for more information. | London |
| A40926 | A40926 is an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. It acts by inhibiting the synthesis of bacterial cell wall. It is also the precursor to dalbavanain. Group: Pharmaceutical. Alternative Names: Dalbavancin Impurity. CAS No. 102961-72-8. Pack Sizes: 100 mg. Product ID: BAT-010110. Molecular formula: C88H101Cl3N10O28. Mole weight: 1853.15. Custom synthesis is available. Send your inquiries for more information. | London |
| A40926-B2 | A40926-B2 is an impurity of A40926, an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. A40926 acts by inhibiting the synthesis of bacterial cell wall. Group: Pharmaceutical. Alternative Names: Antibiotic A-40926 B2. CAS No. 871088-55-0. Pack Sizes: 1mg;1g;10g. Product ID: 871088-55-0. Molecular formula: C84H90Cl2N8O29. Mole weight: 1746.5. Custom synthesis is available. Send your inquiries for more information. | London |
| A40926-ISO B0 | A40926-ISO B0 is an impurity of A40926, an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. A40926 acts by inhibiting the synthesis of bacterial cell wall. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Custom synthesis is available. Send your inquiries for more information. | London |
| A40926-MAG | A40926-MAG is an impurity of A40926, an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. A40926 acts by inhibiting the synthesis of bacterial cell wall. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Custom synthesis is available. Send your inquiries for more information. | London |
| A 410099.1 | A 410099.1 is a high affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Group: Pharmaceutical. Alternative Names: N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride. CAS No. 762274-58-8. Pack Sizes: 1mg;1g;10g. Product ID: 762274-58-8. Molecular formula: C27H40N4O3·HCl. Mole weight: 505.09. Custom synthesis is available. Send your inquiries for more information. | London |
| A-412997 | A-412997. Group: Pharmaceutical. CAS No. 630118-64-8. Pack Sizes: 1mg;1g;10g. Product ID: 630118-64-8. Custom synthesis is available. Send your inquiries for more information. | London |
| A 412997 dihydrochloride | A 412997 dihydrochloride is a potent and selective agonist for the dopamine D4 receptor (Ki = 7.9 and 12.1 nM for human D4 and rat D4, receptors) with no activity for other dopamine receptors. Group: Pharmaceutical. Alternative Names: A-412997 dihydrochloride; A412997 dihydrochloride; A-412997 dihydrochloride; N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide. CAS No. 1347744-96-0. Pack Sizes: 1mg;1g;10g. Product ID: 1347744-96-0. Molecular formula: C19H23N3O.2HCl. Mole weight: 382.33. Custom synthesis is available. Send your inquiries for more information. | London |
| A 419259 | A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM. Group: Pharmaceutical. Alternative Names: A419259; A-419259; RK 20449; RK20449; RK-20449. CAS No. 364042-47-7. Pack Sizes: 1mg;1g;10g. Product ID: 364042-47-7. Molecular formula: C29H34N6O. Mole weight: 482.62. Custom synthesis is available. Send your inquiries for more information. | London |
| A 419259 trihydrochloride | Potent Hck inhibitor (IC50 = 0.43 nM). Also inhibits other Src family kinases (SFKs). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Also inhibits acute myeloid leukemia (AML) stem cell proliferation in vitro and in vivo. Group: Pharmaceutical. Alternative Names: A419259 trihydrochloride; A-419259 trihydrochloride; RK 20449 trihydrochloride; RK20449 trihydrochloride; RK-20449 trihydrochloride. CAS No. 1435934-25-0. Pack Sizes: 1mg;1g;10g. Product ID: 1435934-25-0. Molecular formula: C29H37Cl3N6O. Mole weight: 592. Custom synthesis is available. Send your inquiries for more information. | London |
| A 425619 | A 425619 is a potent and selective TRPV1 antagonist (IC50 = 3-9 nM) that inhibits TRPV1 activation by anandamide and N-arachidonoyl-dopamine. A 425619 exhibits an inhibitory effect against inflammatory, postoperative and osteoarthritic in vivo pain models. Uses: Analgesic. Group: Pharmaceutical. Alternative Names: A-425619; A 425619; A425619; N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea. CAS No. 581809-67-8. Pack Sizes: 1mg;1g;10g. Product ID: 581809-67-8. Molecular formula: C18H14F3N3O. Mole weight: 345.32. Custom synthesis is available. Send your inquiries for more information. | London |
| A 437203 | A 437203 is a selective dopamine (DA) D3 receptor antagonist suited to evaluate the physiological role(s) of D3 receptors. A 437203 shows an approximately 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. Group: Pharmaceutical. Alternative Names: 2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one; 2-(3-(4-(2-tert-butyl-6-trifluoromethylpyrimidin-4-yl)piperazin-1-yl)propylsulfanyl)-3H-pyrimidin-4-one fumarate; A 437203; A-437203; A437203; 1160247-85-7; 220519-07-3 (anhydrous); 220519-06-2 (anhydrous free base). CAS No. 220519-06-2. Pack Sizes: 1mg;1g;10g. Product ID: 220519-06-2. Molecular formula: C20H27F3N6OS. Mole weight: 456.53. Custom synthesis is available. Send your inquiries for more information. | London |
| A-438079 HCl | A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9. Group: Pharmaceutical. Alternative Names: A-438079 HCl; A 438079 HCl; A438079 HCl. CAS No. 899431-18-6. Pack Sizes: 1mg;1g;10g. Product ID: 899431-18-6. Molecular formula: C13H10Cl3N5. Mole weight: 342.61. Custom synthesis is available. Send your inquiries for more information. | London |
| A 438079 hydrochloride | A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores. Group: Pharmaceutical. Alternative Names: 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride; A438079 hydrochloride; A 438079 hydrochloride. CAS No. 899507-36-9. Pack Sizes: 1mg;1g;10g. Product ID: 899507-36-9. Molecular formula: C13H10Cl3N5. Mole weight: 342.61. Custom synthesis is available. Send your inquiries for more information. | London |
| A-443654 | A-443654 is a potent small-molecule inhibitor of all three Akt serine/threonine kinases, induces Akt Ser-473 phosphorylation in all human cancer cell lines tested, including PTEN- and TSC2-deficient lines. It inhibits Akt-dependent signal transduction in cells and in vivo in a dose-responsive manner. Group: Pharmaceutical. Alternative Names: A443564; A-443564; A 443564. CAS No. 552325-16-3. Pack Sizes: 1mg;1g;10g. Product ID: 552325-16-3. Molecular formula: C24H23N5O. Mole weight: 397.47. Custom synthesis is available. Send your inquiries for more information. | London |
| A 484954 | A 484954 is a eukaryotic elongation factor-2 (eEF-2) kinase inhibitor (IC50 = 0.28 μM in enzymatic assay). A 484954 reduces eEF-2 phosphorylation with little effect on cancer cell growth. Group: Pharmaceutical. Alternative Names: A-484954; A 484954; A484954; 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide. CAS No. 142557-61-7. Pack Sizes: 1mg;1g;10g. Product ID: 142557-61-7. Molecular formula: C13H15N5O3. Mole weight: 289.29. Custom synthesis is available. Send your inquiries for more information. | London |
| A-485 | A-485 is an inhibitor of the histone acetyltransferase p300/CBP (IC50 = 60 nM). Group: Pharmaceutical. Alternative Names: (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide. CAS No. 1889279-16-6. Pack Sizes: 100 mg. Product ID: B1370-292260. Molecular formula: C25H24F4N4O5. Mole weight: 536.48. Custom synthesis is available. Send your inquiries for more information. | London |
| A-(4-BROMOPHENYL)-4-METHOXYCINNAMIC ACID | A-(4-BROMOPHENYL)-4-METHOXYCINNAMIC ACID. Group: Pharmaceutical. Alternative Names: A-(4-BROMOPHENYL)-4-METHOXYCINNAMIC ACID. CAS No. 14335-72-9. Pack Sizes: 1mg;1g;10g. Product ID: 14335-72-9. Molecular formula: C16H13BrO3. Mole weight: 333.18. Custom synthesis is available. Send your inquiries for more information. | London |
| A-(4-chloro-3-nitrophenyl)acetamide | A-(4-chloro-3-nitrophenyl)acetamide. Group: Pharmaceutical. CAS No. 5540-60-3. Pack Sizes: 1mg;1g;10g. Product ID: 5540-60-3. Molecular formula: C8H7ClN2O3. Mole weight: 214.6. Custom synthesis is available. Send your inquiries for more information. | London |
| A-54145A | A metabolite of Argatroban, a medication for the prevention and treatment of thrombosis. Group: Pharmaceutical. Alternative Names: Antibiotic A 54145A; A-54145 A. CAS No. 153886-68-1. Pack Sizes: 5 mg. Product ID: BBF-03153. Molecular formula: C10H13NO3S. Mole weight: 227.28. Custom synthesis is available. Send your inquiries for more information. | London |
| A 582941 | A 582941 is a selective α7 nAChR partial agonist which is effetive for both rat and human α7 receptors (Ki = 10.8 and 16.7 nM respectively). Group: Pharmaceutical. Alternative Names: A-582941; A 582941; A582941; Octahydro-2-methyl-5-(6-phenyl-3-pyridazinyl)-pyrrolo[3,4-c]pyrrole; (3aR,6aS)-2-methyl-5-(6-phenylpyridazin-3-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole. CAS No. 848591-90-2. Pack Sizes: 1mg;1g;10g. Product ID: 848591-90-2. Molecular formula: C17H20N4. Mole weight: 280.37. Custom synthesis is available. Send your inquiries for more information. | London |
| A 582941 HCl | A 582941 is a selective α7 nAChR partial agonist which is effetive for both rat and human α7 receptors (Ki = 10.8 and 16.7 nM respectively). Group: Pharmaceutical. Alternative Names: A-582941 HCl; A582941 HCl. Pack Sizes: 1mg;1g;10g. Molecular formula: C17H21ClN4. Mole weight: 316.83. Custom synthesis is available. Send your inquiries for more information. | London |
| A[5']P5[5']A SODIUM SALT | A[5']P5[5']A SODIUM SALT is a paramount biomedical product, standing as a distinguished tool for selective autoimmune conditions and inflammatory dysfunctions. It exhibits its might as a formidable cGAS-STING pathway stimulator. Group: Pharmaceutical. Alternative Names: Adenosine 5'-(hexahydrogen pentaphosphate), 5'.5'-ester with adenosine, pentasodium salt; P1,P5-Di(adenosine-5') pentaphosphate pentasodium salt; Diadenosine pentaphosphate pentasodium salt. CAS No. 4097-4-5. Pack Sizes: 1mg;1g;10g. Product ID: 802535. Molecular formula: C20H24N10Na5O22P5. Mole weight: 1026.28. Custom synthesis is available. Send your inquiries for more information. | London |
| A 61603 hydrobromide | A 61603 hydrobromide is a potent and selective α-adrenoceptor agonist with 35-fold selectivity for α1A over α1B or α1D sites. Activation of the α1A-adrenergic receptor by A 61603 induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro (EC50 = 6.9 nmol/L). Group: Pharmaceutical. Alternative Names: A61603 Hydrobromide; A 61603 Hydrobromide; A-61603 Hydrobromide; N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide hydrobromide. CAS No. 107756-30-9. Pack Sizes: 1mg;1g;10g. Product ID: 107756-30-9. Molecular formula: C14H19N3O3S.HBr. Mole weight: 390.29. Custom synthesis is available. Send your inquiries for more information. | London |
| A66 | Inhibition of p110α alone by A66 treatment is sufficient to block insulin signalling to Akt/PKB in certain cell lines that harbor H1047R mutations in PIK3CA and have high levels of p110α and class-Ia PI3K activity. Group: Pharmaceutical. Alternative Names: A66; A-66; A 66. CAS No. 1166227-08-2. Pack Sizes: 1mg;1g;10g. Product ID: 1166227-08-2. Molecular formula: C17H23N5O2S2. Mole weight: 393.53. Custom synthesis is available. Send your inquiries for more information. | London |
| A-674563 | A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC. Group: Pharmaceutical. Alternative Names: A674563; A 674563; Benzeneethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, (αS)-; (αS)-α-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine; (S)-1-((5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine. CAS No. 552325-73-2. Pack Sizes: 10 mg. Product ID: B0084-307687. Molecular formula: C22H22N4O. Mole weight: 358.44. Custom synthesis is available. Send your inquiries for more information. | London |
| A-674563 dihydrochloride | A-674563, an Akt1 inhibitor with a Ki of 11 nM, is moderately potent against PKA and >30-fold selective for Akt1 over PKC. Group: Pharmaceutical. Alternative Names: A-674563 2HCl; Benzeneethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, hydrochloride (1:2), (αS)-; (αS)-α-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine dihydrochloride; (S)-1-((5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine hydrochloride; A 674563 dihydrochloride; A674563 dihydrochloride. CAS No. 2759293-92-8. Pack Sizes: 1mg;1g;10g. Product ID: 2759293-92-8. Molecular formula: C22H22N4O.2HCl. Mole weight: 431.36. Custom synthesis is available. Send your inquiries for more information. | London |
| A-674563 hydrochloride | A-674563 hydrochloride is a potent, orally available Akt1 inhibitor with Ki of 11 nM. Group: Pharmaceutical. Alternative Names: (S)-1-(5-(3-methyl-1H-indazol-5-yl)pyridin-3-yloxy)-3-phenylpropan-2-amine hydrochloride. CAS No. 2070009-66-2. Pack Sizes: 1mg;1g;10g. Product ID: 2070009-66-2. Molecular formula: C22H23ClN4O. Mole weight: 394.9. Custom synthesis is available. Send your inquiries for more information. | London |
| A6770 | A6770, a potentially key metabolite of THI, induces [3H]dhS1P increase and is a potent and orally active inhibitor of sphingosine 1-phosphate lyase (S1PL). A6770 is phosphorylated, and the phosphorylated form directly inhibits S1P lyased. Group: Pharmaceutical. Alternative Names: Ethanone, 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]-; 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]ethan-1-one. CAS No. 1331754-16-5. Pack Sizes: 1mg;1g;10g. Product ID: 1331754-16-5. Molecular formula: C6H8N2O2. Mole weight: 140.14. Custom synthesis is available. Send your inquiries for more information. | London |
| A68930 | A68930 is a dopamine D1 receptor agonist that can be used in the study of bronchiectasis. Uses: Dopamine agonists. Group: Pharmaceutical. Alternative Names: 5,6-Dihydroxy-3-phenyl-1-aminomethylisochroman; 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-phenyl-, (1R-cis)-; (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol; (1R,3S)-1-(aminomethyl)-3-phenyl-3,4-dihydro-1H-2-benzopyran-5,6-diol. CAS No. 130465-45-1. Pack Sizes: 1mg;1g;10g. Product ID: 130465-45-1. Molecular formula: C16H17NO3. Mole weight: 271.31. Custom synthesis is available. Send your inquiries for more information. | London |
| A 68930 hydrochloride | A 68930 hydrochloride is a potent and selective dopamine D1-like receptor agonist (EC50 = 2.1 and 3910 nM for D1-like and D2-like receptors, respectively). Group: Pharmaceutical. Alternative Names: A-68930 hydrochloride; A 68930 hydrochloride; A68930 hydrochloride; cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride; (1R,3S)-1-(aminomethyl)-3-phenyl-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride. CAS No. 130465-39-3. Pack Sizes: 1mg;1g;10g. Product ID: 130465-39-3. Molecular formula: C16H17NO3.HCl. Mole weight: 307.78. Custom synthesis is available. Send your inquiries for more information. | London |
| A7132 | A7132 is an antibacterial agent and possesses broad and potent antibacterial activity. Group: Pharmaceutical. Alternative Names: 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid. CAS No. 100490-21-9. Pack Sizes: 1mg;1g;10g. Product ID: 100490-21-9. Molecular formula: C19H16F2N4O3. Mole weight: 386.35. Custom synthesis is available. Send your inquiries for more information. | London |
| A 71378 | A 71378 is a high potency, selectivity CCK-A receptors agonist with the IC50 values of 0.4 nM, 300 nM, and 1,200 nM for the pancreatic CCK-A, cortical CCK-B, and gastrin receptor, respectively. Group: Pharmaceutical. Alternative Names: A-71378; Desamino-tyr(SO3H)-nle-gly-trp-nle-(N-methyl)asp-phe-NH2. CAS No. 127902-33-4. Pack Sizes: 1mg;1g;10g. Product ID: 127902-33-4. Molecular formula: C48H62N8O13S. Mole weight: 991.12. Custom synthesis is available. Send your inquiries for more information. | London |
| A-71623 | A-71623 is a tetrapeptide and acts as a potent CCK1 agonist (IC50 = 3.7 nM) displaying 1200-fold selectivity over the CCK2 receptor. A-71623 is used to suppress appetite and reduce food intake following central or peripheral administration. Group: Pharmaceutical. Alternative Names: A 71623; A-71623; A71623; N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-N6-[[(2-methylphenyl)amino]carbonyl]-L-lysyl-L-α-aspartyl-Nα-methyl-L-phenylalaninamide. CAS No. 130408-77-4. Pack Sizes: 1mg;1g;10g. Product ID: 130408-77-4. Molecular formula: C44H56N8O9. Mole weight: 840.97. Custom synthesis is available. Send your inquiries for more information. | London |
| A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist. Its IC50 values are 18 and 40 nM for rat and human receptors respectively measured by agonist-stimulated changes in intracellular calcium concentrations. It displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. It reduces nociception in animal models of persistent neuropathic and inflammatory pain. It showed weak or no activity (IC(50) > 10 muM) at other P2 receptors and an array of other neurotransmitter and peptide receptors, ion channels, reuptake sites, and enzymes. It potently blocked agonist-evoked IL-1beta release (IC(50) = 156 nM) and pore formation (IC(50) = 92 nM) in differentiated human THP-1 cells. It produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Uses: A-740003 produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Group: Pharmaceutical. Alternative Names: A-740003; A 740003; A740003; N-[1-[[(Cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide;N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide. CAS No. 861393-28-4. Pack Sizes: 1mg;1g;10g. Product ID: 861393-28-4. Molecular formula: C26H30N6O3. Mole weight: 474.55. Custom synthesis is available. Send your inquiries for more information. | London |
| A-769662 | A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM in cell-free assays, little effect on GPPase/FBPase activity. Group: Pharmaceutical. Alternative Names: 4-Hydroxy-3-(2'-hydroxy-[1,1'-biphenyl]-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile. CAS No. 844499-71-4. Pack Sizes: 1mg;1g;10g. Product ID: 844499-71-4. Molecular formula: C20H12N2O3S. Mole weight: 360.4. Custom synthesis is available. Send your inquiries for more information. | London |
| A-770041 | A-770041 is an selective and orally bioavailable pyrazolo[3,4-d]pyrimidine exhibiting selectivity for Lck compared with previously reported compounds. It is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling. It is currently in the preclinical developlent stage and no clinical data are available. Group: Pharmaceutical. Alternative Names: A-770041; A 770041; A770041. CAS No. 869748-10-7. Pack Sizes: 1mg;1g;10g. Product ID: 869748-10-7. Molecular formula: C34H39N9O3. Mole weight: 621.73. Custom synthesis is available. Send your inquiries for more information. | London |
| A-77-01 | A-77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5( IC50 =25nM). Uses: Potent alk5 inhibitor. Group: Pharmaceutical. Alternative Names: A77-01; A 77-01; A-77-01. 4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-quinoline;4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline. CAS No. 607737-87-1. Pack Sizes: 1mg;1g;10g. Product ID: 607737-87-1. Molecular formula: C18H14N4. Mole weight: 286.34. Custom synthesis is available. Send your inquiries for more information. | London |
| A 77636 hydrochloride | A 77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist (pEC50 = 8.97 and < 5 for D1-like and D2-like receptors, respectively). A 77636 exhibits anti-Parkinsonian activity following oral administration in vivo. Uses: Potential treatment of neurological disorders. Group: Pharmaceutical. Alternative Names: A-77636 hydrochloride; A77636 hydrochloride; A77636 hydrochloride; (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride. CAS No. 145307-34-2. Pack Sizes: 1mg;1g;10g. Product ID: 145307-34-2. Molecular formula: C20H27NO3.HCl. Mole weight: 365.9. Custom synthesis is available. Send your inquiries for more information. | London |
| A 779 | A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor) (IC50 = 0.3 nM) with no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. Group: Pharmaceutical. Alternative Names: A-779; A779; (D-Ala7)-Angiotensin I/II (1-7); Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH; 5-L-isoleucine-7-D-alanine-1-7-angiotensin II; 7-Ala-angiotensin (1-7); A 778; A 779; A-778; A779 peptide; angiotensin (1-7), Ala(7)-; angiotensin (1-7), alanyl(7)-; Asp-Arg-Val-Tyr-Ile-His-Ala; aspartyl-arginyl-valyl-tyrosyl-isoleucyl-histidyl-alanine. CAS No. 159432-28-7. Pack Sizes: 10 mg. Product ID: BAT-006218. Molecular formula: C39H60N12O11. Mole weight: 872.97. Custom synthesis is available. Send your inquiries for more information. | London |
| A 784168 | A 784168 is a potent and selective TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin) exhibiting no activity against a range of receptors such as TRPA1, GABA, opioid, and purinergic receptors. Group: Pharmaceutical. Alternative Names: A 784168; A784168; A-784168; 3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide; 1-[3-(trifluoromethyl)pyridin-2-yl]-N-[4-(trifluoromethylsulfonyl)phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide. CAS No. 824982-41-4. Pack Sizes: 1mg;1g;10g. Product ID: 824982-41-4. Molecular formula: C19H15F6N3O3S. Mole weight: 479.4. Custom synthesis is available. Send your inquiries for more information. | London |
| A 790742 | A 790742. Group: Pharmaceutical. CAS No. 854755-48-9. Pack Sizes: 1mg;1g;10g. Product ID: 854755-48-9. Molecular formula: C49H65N7O7. Mole weight: 864.1. Custom synthesis is available. Send your inquiries for more information. | London |
| A 792611 | A 792611. Group: Pharmaceutical. CAS No. 854758-17-1. Pack Sizes: 1mg;1g;10g. Product ID: 854758-17-1. Molecular formula: C47H60N6O6. Mole weight: 805. Custom synthesis is available. Send your inquiries for more information. | London |
| A-7 hydrochloride | A-7 hydrochloride is a cell-permeable antagonist of calmodulin that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Calmodulin is a calcium-dependent protein expressed in all eukaryotic cells, modulating the interaction of calcium with target proteins. Group: Pharmaceutical. Alternative Names: A-7 monohydrochloride; A 7 hydrochloride; A7 hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide monoydrochloride. CAS No. 79127-24-5. Pack Sizes: 1mg;1g;10g. Product ID: 79127-24-5. Molecular formula: C20H29ClN2O2S.HCl. Mole weight: 433.44. Custom synthesis is available. Send your inquiries for more information. | London |
| A-802715 | A802715, a methylxanthine derivative, is an anti-tumor agent with a TD50 (toxic dose of 50%) of 0.9-1.1 mM. Group: Pharmaceutical. Alternative Names: 1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propylpurine-2,6-dione; 1-(5-hydroxy-5-methyl)hexyl-3-methyl-7-propylxanthine; A 80 2715; A 802715; A-802715. CAS No. 107767-58-8. Pack Sizes: 1mg;1g;10g. Product ID: 107767-58-8. Molecular formula: C16H26N4O3. Mole weight: 322.4. Custom synthesis is available. Send your inquiries for more information. | London |
| A-803467 | A-803467 is a sodium channel blocker that potently blocks tetrodotoxin-resistant currents (IC50=140 nM). Group: Pharmaceutical. Alternative Names: A-803467; A 803467; A803467. CAS No. 944261-79-4. Pack Sizes: 1mg;1g;10g. Product ID: 944261-79-4. Molecular formula: C19H16ClNO4. Mole weight: 357.79. Custom synthesis is available. Send your inquiries for more information. | London |
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