BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Shikonin | Shikonin belongs naphthoquinone isolated from Arnebia sp. It is used as an anti-inflammatory treatment in traditional chinese medicine (TCM). It inhibits chemokine receptor function and suppresses HIV-1. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 54952-43-1. Pack Sizes: 100 mg. Product ID: B1370-094286. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| (S)-homo-β-alanine | (S)-Homo-β-alanine, an amino acid occurring naturally, acts as an intermediary in thymine metabolism. Its potential to regulate oxidative stress and inflammation marks it as a prospective treatment for cardiovascular disease and hypertension. Also, research suggests its involvement in the synthesis of neurotransmitter gamma-aminobutyric acid (GABA) in the brain. Group: Pharmaceutical. CAS No. 3775-72-2. Pack Sizes: 10 g. Product ID: B2699-114069. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SHP099 | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo. Group: Pharmaceutical. CAS No. 1801747-42-1. Pack Sizes: 20 mg. Product ID: B0084-007855. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SHP099 HCl | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo. Group: Pharmaceutical. CAS No. 1801747-11-4. Pack Sizes: 500 mg. Product ID: B2693-007852. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Siamenoside I | Siamenoside I is natural sweetener found in the fruit of Siraitia grosvenorii. It is used as a natural sweetener in China. Group: Pharmaceutical. CAS No. 126105-12-2. Pack Sizes: 20 mg. Product ID: B0005-407256. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Ibrutinib | (S)-Ibrutinib is a highly selective Bruton's tyrosine kinase (Btk) irreversible inhibitor. Group: Pharmaceutical. CAS No. 936563-97-2. Pack Sizes: 10 mg. Product ID: B1370-472300. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sideroxylonal A | Sideroxylonal A can be extracted from the branch of Eucalyptus globulus. Group: Pharmaceutical. CAS No. 145382-68-9. Pack Sizes: 1 mg. Product ID: NP4738. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silidianin | Silydianin is an active constituent of Silybium marianum and is known the exhibit anti-inflammatory activity which regulates caspase-3 activation which affects cell membranes and acts as a free radical scavenger. Group: Pharmaceutical. CAS No. 29782-68-1. Pack Sizes: 100 mg. Product ID: B2703-464840. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silmitasertib | Silmitasertib is an orally bioavailable inhibitor of CK2 with potential antineoplastic activity. It inhibits proliferation in cancer cell lines overexpressing CK2. It suppresses survival and induces apoptosis of cancer stem cells including glioblastomas and acute myeloid leukemia cells. Group: Pharmaceutical. CAS No. 1009820-21-6. Pack Sizes: 500 mg. Product ID: B2693-286324. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silodosin Dehydro Impurity | An impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Group: Pharmaceutical. CAS No. 175870-21-0. Pack Sizes: 50 mg. Product ID: B2694-479611. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silodosin Impurities | Silodosin Impurities, integral to the quality assessment in pharmaceuticals, play a vital role in scrutinizing the purity and stability of Silodosin, the alpha-1 adrenergic receptor antagonist utilized in benign prostatic hyperplasia (BPH) treatment. These substances underscore therapeutic efficacy and patient safety, optimizing the clinical effectiveness of Silodosin. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silodosin S-Isomer | An isomer of Silodosin, which is used in the treatment of the symptoms of an enlarged prostate (benign prostatic hyperplasia; BPH) in men. Group: Pharmaceutical. CAS No. 2182279-45-2. Pack Sizes: 50 mg. Product ID: B2694-343858. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silybin A | Silymarin, isolated from the herb of Silybum marianum (L.) Gaertn, is an antioxidant or free radical scavenger. Silymarin and Prunella vulgaris improve antioxidant status in blood and liver, and positively affect plasma lipoprotein profile in an experimental model of dietary induced hypertriglyceridemia. Both in vitro and animal research suggest that Silymarin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silymarin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells. Silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile. Treatment with silymarin may reduce the lipoperoxidation of cell membranes and insulin resistance, significantly decreasing endogenous insulin overproduction and the need for exogenous insulin administration. Silybin is a natural compound also can be used in cosmetics material. Uses: Protective agents. Group: Pharmaceutical. CAS No. 22888-70-6. Pack Sizes: 100 g. Product ID: NP1920. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silybin B | An isomer of Silybin. Silybin, extracted from Silybum, is the major active constituent of silymarin. Uses: Antineoplastic agents, phytogenic. Group: Pharmaceutical. CAS No. 142797-34-0. Pack Sizes: 25 mg. Product ID: B2703-362209. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Silychristin | Silychristin is a new natural product has been isolated from silymarin, the hepatoprotective extract of milk thistle (Silybum marianum) fruits. Silychristin has been shown to be an antihepatotoxic flavonolignan. Group: Pharmaceutical. CAS No. 33889-69-9. Pack Sizes: 10 mg. Product ID: B0005-464841. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simeprevir | Simeprevir plays an important role in HCV replication. Data from phase I and II clinical trials of TMC-435350 (TMC 435350; TMC 435; TMC-435350) to date have shown that this agent is well tolerated as a once-daily oral therapy and provides potent antiviral activity in HCV genotype 1-infected subjects, with restoration of liver enzymes and no evidence of viral breakthrough. Group: Pharmaceutical. CAS No. 923604-59-5. Pack Sizes: 100 mg. Product ID: B2693-433027. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simethicone | Simethicone is an antifoaming agent. Group: Pharmaceutical. CAS No. 8050-81-5. Pack Sizes: 1 kg. Product ID: B1370-304245. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin-[d3] | An isotope labelled of Simvastin. Simvastatin is a lipid-lowering medication and the primary uses of simvastatin are to treat dyslipidemia. Group: Pharmaceutical. CAS No. 1002347-61-6. Pack Sizes: 50 mg. Product ID: BLP-013128. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity B | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 145576-25-6. Pack Sizes: 100 mg. Product ID: B2694-223423. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity C | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 210980-68-0. Pack Sizes: 100 mg. Product ID: B2694-260207. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity D | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 476305-24-5. Pack Sizes: 10 mg. Product ID: B2694-263916. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity F | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 79952-44-6. Pack Sizes: 50 mg. Product ID: B2694-261180. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity G | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 1449248-72-9. Pack Sizes: 25 mg. Product ID: B2694-479627. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity H | An intermediate in the synthesis of Simvastatin, Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 79952-42-4. Pack Sizes: 50 mg. Product ID: B2694-257205. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity I | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 79902-42-4. Pack Sizes: 10 mg. Product ID: B2694-334169. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin EP Impurity J | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 864357-88-0. Pack Sizes: 50 mg. Product ID: B2694-121702. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin hydroxy acid sodium salt | A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. CAS No. 101314-97-0. Pack Sizes: 100 mg. Product ID: B2694-479622. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Simvastatin Impurities | Simvastatin Impurities are pivotal in the refinement and quality control of simvastatin, a widely used medication for lowering cholesterol and managing cardiovascular diseases. These impurities, studied to enhance drug efficacy and safety, play a crucial role in advancing pharmaceutical formulations in the treatment of hypercholesterolemia and related disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sinapaldehyde glucoside | Sinapaldehyde glucoside, also called Sinapaldehyde 4-O-beta-D-glucopyranoside, is a natural plant isolated from the barks of Phellodendron amurense. Group: Pharmaceutical. CAS No. 154461-65-1. Pack Sizes: 1 mg. Product ID: NP5417. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sinapine | Sinapine is an alkaloid isolated from cruciferous species with antioxidant and radio-protective activities. Group: Pharmaceutical. CAS No. 18696-26-9. Pack Sizes: 25 mg. Product ID: B2703-171989. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sinapultide | Sinapultide is a synthetic protein that mimics human lung surfactant protein B. This compound is undergoing preclinical development in lung disorders, and is planned for a phase III clinical trial for aerosol delivery system (ADS) in Respiratory distress syndrome. Group: Pharmaceutical. CAS No. 138531-07-4. Pack Sizes: 10 mg. Product ID: BAT-010102. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sincalide | It is a synthetically-prepared C-terminal octapeptide of cholecystokinin.Sincalide (INN) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin. Group: Pharmaceutical. CAS No. 25126-32-3. Pack Sizes: 5 mg. Product ID: BAT-010658. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Indacaterol | An isomerous impurity of Indacaterol. Indacaterol is an ultra-long-acting β-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Group: Pharmaceutical. CAS No. 1235445-80-3. Pack Sizes: 1 mg. Product ID: B1217-007228. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sinensetin | Sinensetin is a natural flavonoid compound isolated from the fruit of Citrus aurantium L. Sinensetin exhibits the anti-inflammatory, antimutagenic and anticancer activities. Uses: Antimutagenic, anticancer, anti-inflammatory. Group: Pharmaceutical. CAS No. 2306-27-6. Pack Sizes: 100 mg. Product ID: NP2524. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sinensin | Sinensin is a flavonoid compound found in the herbs of Cudrania cochinchinensis. Group: Pharmaceutical. CAS No. 28189-90-4. Pack Sizes: 5 mg. Product ID: NP2162. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SINOACUTINE | Sinoacutine, a natural alkaloid sourced from flora, boasts analgesic and anti-inflammatory properties backed by clinical research. The compound's potential in treating inflammatory diseases, including rheumatoid arthritis, has been subject to investigations. Sinoacutine's efficacy in regulating immune responses is attributable to its ability to obstruct the release of inflammatory cytokines, rendering it a viable candidate in the development of novel anti-inflammatory agents. Group: Pharmaceutical. CAS No. 4090-18-0. Pack Sizes: 5 mg. Product ID: NP0371. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sinomenine hydrochloride | Sinomenine HCl could improve survival, reduce organ damage, and attenuate the release of inflammatory cytokines induced by CLP, at least in part through regulating autophagy activities. Uses: Anti-tumor and anti-metastasis. Group: Pharmaceutical. CAS No. 6080-33-7. Pack Sizes: 100 g. Product ID: NP0538. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Siponimod | Siponimod is a selective S1P1 and S1P5 agonist with EC50 of 0.39 nM and 0.98 nM, respectively. It has been approved by US FDA for the treatment of patients with active secondary progressive multiple sclerosis (SPMS). Group: Pharmaceutical. CAS No. 1230487-00-9. Pack Sizes: 100 mg. Product ID: B0084-463380. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Siramesine hydrochloride | Siramesine hydrochloride is the hydrochloride salt form of Siramesine. Siramesine is a selective sigma-2 receptor agonist with potent anticancer activity in vivo. It was originally devevloped for treating depressant. Group: Pharmaceutical. CAS No. 224177-60-0. Pack Sizes: 100 mg. Product ID: B2693-474703. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SIS3 HCl | SIS3 is a potent and specific inhibitor of Smad3 via inhibiting the effects of TGF-β1. SIS3 inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation with no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. It inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts. Group: Pharmaceutical. CAS No. 521984-48-5. Pack Sizes: 20 mg. Product ID: B0084-121733. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sisomicin Impurities | Sisomicin Impurities are crucial in the biomedical field for quality control and validation in antibiotic production. These impurities help in the synthesis of analogs to treat multidrug-resistant bacterial infections. Their role is vital in ensuring the efficacy and safety of aminoglycoside antibiotics used in severe bacterial disease management. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sissotrin | Sissotrin is a natural flavonoid isolated from the herbs of Trifolium pratense L. It can impair glucose tolerance. Group: Pharmaceutical. CAS No. 5928-26-7. Pack Sizes: 1 mg. Product ID: NP2178. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sisunatovir | Sisunatovir is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. Sisunatovir exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Group: Pharmaceutical. CAS No. 1903763-82-5. Pack Sizes: 50 mg. Product ID: B1370-386470. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitafloxacin Impurities | Sitafloxacin Impurities are integral to the scrupulous assessment of Sitafloxacins purity and pharmacological robustness, a complex antibacterial used against varied bacterial strains. Their accurate identification and quantification ensure both safety and therapeutic potency, crucial for addressing community-acquired pneumonia and intricate urinary tract infections, thus validating its clinical application. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin | Sitagliptin (MK 0431) is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts. Sitagliptin is used as a hypoglycemic agent to treat type 2 diabetes. Uses: The treatment of type 2 diabetes. Group: Pharmaceutical. CAS No. 486460-32-6. Pack Sizes: 500 mg. Product ID: BBF-05866. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin EP Impurity A Phosphate | Sitagliptin EP Impurity A Phosphate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 823817-58-9. Pack Sizes: 100 mg. Product ID: B0017-479659. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin EP Impurity B | Sitagliptin EP Impurity B is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 486460-31-5. Pack Sizes: 25 mg. Product ID: B2694-479656. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin EP Impurity B Phosphate | Sitagliptin EP Impurity B Phosphate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 1345822-87-8. Pack Sizes: 10 mg. Product ID: B2694-179047. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin EP Impurity C | Sitagliptin EP Impurity C is a impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 945261-48-3. Pack Sizes: 100 mg. Product ID: B2694-352408. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin EP Impurity C Phosphate | Sitagliptin EP Impurity C Phosphate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 1345822-86-7. Pack Sizes: 30 mg. Product ID: B2694-174790. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin FP Impurity B | Sitagliptin FP Impurity B is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 2088771-61-1. Pack Sizes: 5 mg. Product ID: B2694-334170. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin FP Impurity E Hydrochloride | Sitagliptin EP Impurity E is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 1204818-19-8. Pack Sizes: 1 g. Product ID: BAT-008056. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin Fumarate Adduct (Mixture of Diastereomers) | Sitagliptin Fumarate Adduct is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 2088771-60-0. Pack Sizes: 50 mg. Product ID: B2694-032361. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin Impurities | Sitagliptin Impurities function as essential constituents in the biomedical sector, facilitating the meticulous evaluation of Sitagliptin's purity and safety. Integral to quality assurance during drug development, they ascertain therapeutic efficacy for type 2 diabetes patients by verifying the lack of undesirable byproducts, upholding superior pharmaceutical benchmarks. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin Impurity 40 HCl | Sitagliptin Impurity 40 HCl is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 1374985-05-3. Pack Sizes: 500 mg. Product ID: B2694-186710. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin phenylcrotonyl analog | Sitagliptin phenylcrotonyl analog is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 1253056-18-6. Pack Sizes: 10 mg. Product ID: B0017-479654. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin Phosphate Monohydrate | Sitagliptin Phosphate Monohydrate is the phosphate salt form of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 654671-77-9. Pack Sizes: 100 g. Product ID: B2692-335254. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitagliptin styrylacetyl analog | Sitagliptin styrylacetyl analog is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Group: Pharmaceutical. CAS No. 1803026-58-5. Pack Sizes: 10 mg. Product ID: B0017-004064. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sitostenone | Sitostenone is isolated from the roots of Xanthium sibiricum. Sitostenone has antioxidant activity and can be used in the treatment of androgen-dependent diseases, especially benign prostatic hyperplasia. Group: Pharmaceutical. CAS No. 1058-61-3. Pack Sizes: 5 mg. Product ID: NP6070. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SKF-86002 | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Group: Pharmaceutical. CAS No. 72873-74-6. Pack Sizes: 300 mg. Product ID: B0084-195907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SKQ1 | SKQ1, also known as plastoquinonyl decyltriphenyl phosphonium or PDTP, is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. Group: Pharmaceutical. CAS No. 934826-68-3. Pack Sizes: 25 mg. Product ID: B0084-462254. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SLC-0111 | SLC-0111, also known as U-104, MST-104 and NSC 213841, is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). U-104 associates with CAIX/CAXII only under hypoxic conditions in vivo, reducing extracellular acidity and resulting in significant inhibition of tumor growth and metastasis in experimental models. Group: Pharmaceutical. CAS No. 178606-66-1. Pack Sizes: 50 mg. Product ID: B0084-007841. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SLF | SLF is a cell-permeable analog of FK-506, an immunosuppressant with high affinity for FK-506 binding protein 12 (FKBP12). SLF binds tightly to FKBP but lacks the ability to inhibit calcineurin. Group: Pharmaceutical. CAS No. 195513-96-3. Pack Sizes: 100 mg. Product ID: B1370-291436. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Slv319 | Slv319 is a potent antagonist of CB1 recceptor (Ki = 7.8 nM) used for the treatment of neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction and gastrointestinal disorders, as well as inhibits CP 55,940-induced hypotension and WIN 55,212-2-induced hypothermia in vivo. Group: Pharmaceutical. CAS No. 362519-49-1. Pack Sizes: 25 mg. Product ID: B0084-112540. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SM-102 | SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles which is used in the Moderna COVID-19 vaccine. Group: Pharmaceutical. CAS No. 2089251-47-6. Pack Sizes: 100 mg. Product ID: B2699-358154. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SM-164 | SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein and binds to cIAP-1 and cIAP-2 proteins. It is developed as an anticancer agent. It plays its antitumor roles through inducing degradation of cellular inhibitor of apoptosis protein (cIAP)-1/2, antagonizing X-linked inhibitor of apoptosis protein (XIAP) and inducing TNFα-dependent apoptosis in tumor cells. It binds to cIAP-1 protein containing bothBIR2 and BIR3 domains, cIAP-2 BIR3 protein and XIAP protein containing both BIR2 and BIR3 domains. Group: Pharmaceutical. CAS No. 957135-43-2. Pack Sizes: 5 mg. Product ID: B2693-463701. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Smad3 Inhibitor, SIS3 | Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Group: Pharmaceutical. CAS No. 1009104-85-1. Pack Sizes: 25 mg. Product ID: B0084-310534. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SMCC | SMCC is a heterobifunctional protein crosslinker for antibody-drug-conjugation (ADC). Group: Pharmaceutical. CAS No. 64987-85-5. Pack Sizes: 5 g. Product ID: BAT-006461. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-(+)-Mephenytoin | (S)-(+)-Mephenytoin is an S-isomer of Mephenytoin, which is known to target sodium channel protein type 5 subunit alpha. Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. It can be used to screen for such mutations by assaying its metabolites in urine. Group: Pharmaceutical. CAS No. 70989-04-7. Pack Sizes: 50 mg. Product ID: B1370-204709. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Metoprolol | (S)-Metoprolol is the (S)-Enantiomer of Metoprolol, a β1 receptor blocker medication. Group: Pharmaceutical. CAS No. 81024-42-2. Pack Sizes: 2 mg. Product ID: B2694-407602. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
Would you like to list your products on UK Chemical Suppliers?
Our database is helping our users find suppliers everyday.