BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
×
Product
Description
Suppliers Website
N,N-dimethyldodecan-1-amine oxide
N,N-dimethyldodecan-1-amine oxide is a frequently-used amine oxide surfactant. It is strongly hydrophilic, and it forms normal micelles and normal liquid crystalline phases. Group: Pharmaceutical. CAS No. 1643-20-5. Pack Sizes: 100 g. Product ID: B4059-304397. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N,N-Dimethyl-L-Tyrosine
N,N-Dimethyl-L-Tyrosine, a derivative of the amino acid tyrosine, has been a subject of interest in the research field due to its key role in elucidating amino acid metabolism. Additionally, it has been extensively studied for its precursor role in the synthesis of well-known neurotransmitters like dopamine and norepinephrine, thereby finding novel therapeutic applications in the treatment of neurodegenerative disorders such as Parkinson's disease and depression. The significance of this chemical compound could not be overstated in the realm of medicinal research. Group: Pharmaceutical. CAS No. 17350-74-2. Pack Sizes: 50 mg. Product ID: B2699-052153. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N,N-dimethyloctadecanamide
N,N-dimethyloctadecanamide (CAS# 3886-90-6 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 3886-90-6. Pack Sizes: 100 mg. Product ID: B2699-115089. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N,N'-Ethylenebisoleamide
N,N'-Ethylenebisoleamide is a compound with surfactant and emulsifying properties, extensively used in biomedicine. Its multipurpose functionality includes being an antifungal, anticancer and antiviral agent, and its feasibility against life-altering diseases such as HIV, influenza, and cancer are being researched. Group: Pharmaceutical. CAS No. 110-31-6. Pack Sizes: 10 g. Product ID: B2699-013796. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Nitrosocytisine
N-Nitrosocytisine is a derivative of Cytisine, which is a nicotinic acetylcholine receptor (nAChR) agonist. Group: Pharmaceutical. CAS No. 19634-60-7. Pack Sizes: 100 mg. Product ID: B1370-343453. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Nitrosohexamethyleneimine
N-Nitrosohexamethyleneimine (CAS# 932-83-2 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 932-83-2. Pack Sizes: 100 mg. Product ID: B2699-111644. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Nitroso Tamsulosin
An impurity of Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-070217. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N,N,N,N-Tetraacetyl chitotetraose
N,N,N,N-Tetraacetyl Chitotetraose is an intriguing biomedical compound with prodigious prowess in the research of immunology and pioneering drug delivery systems. Group: Pharmaceutical. CAS No. 2706-65-2. Pack Sizes: 10 mg. Product ID: B1370-177615. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N,N,N',N'-Tetramethyl-1,5-pentanediamine
N,N,N',N'-Tetramethyl-1,5-pentanediamine (CAS# 44994-28-7 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 44994-28-7. Pack Sizes: 100 g. Product ID: B2699-054518. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N,N'-Thiobisphthalimide
N,N'-Thiobisphthalimide. Group: Pharmaceutical. CAS No. 7764-29-6. Pack Sizes: 1 g. Product ID: B0001-072262. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nobiletin
Nobiletin is a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities. Nobiletin has anti-hemagglutination, anti-thrombosis, anti-fungal, anti-allergic, anti-cholinesterase and anti-epileptic effects. It is a carbohydrate metabolism promoter. Uses: Anticancer. Group: Pharmaceutical. CAS No. 478-01-3. Pack Sizes: 1 g. Product ID: NP1887. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nociceptin
Nociceptin, a 17 amino acid neuropeptide involved in a variety of biological systems, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic. Group: Pharmaceutical. CAS No. 170713-75-4. Pack Sizes: 5 mg. Product ID: BAT-006193. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nodakenetin
Nodakenetin is a coumarin isolated from Angelica decursiva, exhibiting antioxidant, anti-inflammatory and antitumor activities. Study showed that nodakenetin triggered the G2/M cell cycle arrest of HL-60 leukemia cells in a dose-dependent manner as evidenced from flow cytometry. Uses: Antiproliferative, anti-inflammatory. Group: Pharmaceutical. CAS No. 495-32-9. Pack Sizes: 10 mg. Product ID: NP1096. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nodakenin
Nodakenin is an important natural resource and medicinal material with anti-allergic and anti-inflammatory activities. Group: Pharmaceutical. CAS No. 495-31-8. Pack Sizes: 25 mg. Product ID: B2703-465430. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N,O-Diacetate Isoacyclovir
An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. CAS No. 91702-60-2. Pack Sizes: 10 mg. Product ID: B0093-466141. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nodosin
Nodosin is isolated from the herbs of Isodon serra. Uses: Anti-inflammatory; antibacterial; insect growth inhibitor. Group: Pharmaceutical. CAS No. 10391-09-0. Pack Sizes: 5 mg. Product ID: NP1273. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nogo-66 (1-40)
Nogo-66 (1-40), a peptide fragment corresponding to residues 1-40 of Nogo-66, acts as a competitive antagonist at the Nogo-66 receptor (NgR), which blocks Nogo-66 or CNS myelin inhibition of axonal outgrowth in vitro, demonstrating that NgR mediates a significant portion of axonal outgrowth inhibition by myelin. Group: Pharmaceutical. CAS No. 475221-20-6. Pack Sizes: 1 mg. Product ID: BAT-006216. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nolatrexed dihydrochloride
Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II study of nolatrexed in 2007 in advanced HCC patients demonstrated minimal activity and significant stomatitis. Group: Pharmaceutical. CAS No. 152946-68-4. Pack Sizes: 50 mg. Product ID: B0084-059576. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nomegestrol Impurities
Nomegestrol Impurities, integral to the biomedical sphere, underpin quality assurance and validation of nomegestrol acetate, a progestin pivotal for oral contraceptives and hormone therapies. Their detection and quantification are vital for ensuring drug safety and efficacy, thus serving as indispensable elements in pharmaceutical scrutiny and regulatory adherence. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nonacosan-15-one
Nonacosan-15-one (CAS# 2764-73-0 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 2764-73-0. Pack Sizes: 100 g. Product ID: B2699-177852. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nonanedione Impurities
Nonanedione Impurities play a significant role in the development and synthesis of novel pharmaceutical agents. These impurities assist in refining drug formulation processes, ensuring the efficacy and safety of medications aimed at treating conditions such as cardiovascular diseases and metabolic disorders. Their presence during the synthesis is crucial for quality control and drug validation. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nonapeptide-1
Nonapeptide-1 is a skin-lightening peptide that prevents melanin synthesis and unwanted pigmentation. It is used as an additive in whitening or spot corrective products. Nonapeptide-1 is a biomimetic peptide that is a good match for the MC1 receptor on melanocytes and thus acts as an antagonist to melanocytotropic hormone, competitively binding to the MC1 receptor and preventing further activation of tyrosinase to produce melanin. Uses: Skin lightening additive. Group: Pharmaceutical. CAS No. 158563-45-2. Pack Sizes: 100 mg. Product ID: BAT-010784. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nonatriacontane
Nonatriacontane can be used as a surfactant in detergents and other cleaning products due to its ability to reduce surface tension and enhance the ability of the product to dissolve in water. Group: Pharmaceutical. CAS No. 7194-86-7. Pack Sizes: 100 mg. Product ID: B1370-326173. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nonatrienal Impurities
Nonatrienal Impurities, integral to the biomedical sphere, excel in the calibration and validation of analytical techniques targeting volatile organic compounds. Their detailed characterization enriches lipid peroxidation research and aids in unveiling oxidative stress-linked diseases, such as cardiovascular and neurodegenerative disorders, thereby propelling scientific comprehension forward. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nonivamide Impurities
Nonivamide Impurities, essential to biomedical scrutiny, meticulously assess the purity and safety of capsaicin-based formulations. Integral to chronic pain and inflammatory research, they ensure therapeutic effectiveness and patient safety. This rigorous examination substantially advances understanding and therapeutic approaches for related pathophysiological conditions, thereby marking a significant leap in medical science. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nonoxynol-5
Nonylbenzene-PEG5-OH is a polyethylene glycol (PEG)-based PROTAC linker. Nonylbenzene-PEG5-OH can be used in the synthesis of a series of PROTACs. Group: Pharmaceutical. CAS No. 20636-48-0. Pack Sizes: 1 g. Product ID: B2693-277035. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Noopept
Noopept is a nootropic and neuroprotective drug that normalizes the balance of the pro- and antioxidant systems. Noopept modulates a variety of physiological functions including cognition and anxiety. Noopept significantly weakens streptozotocin-Induced diabetes in rats. Group: Pharmaceutical. CAS No. 157115-85-0. Pack Sizes: 5 g. Product ID: B0084-059908. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Noradrenalone Hydrochloride
An impurity of Norepinephrine. Norepinephrine, also known as noradrenaline, is a marker for catecholamine-secreting tumors such as pheochromocytoma, paraganglioma, and neuroblastoma. Group: Pharmaceutical. CAS No. 5090-29-9. Pack Sizes: 1 g. Product ID: B1370-471058. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norbornane
Norbornane is a useful research chemical. Group: Pharmaceutical. CAS No. 279-23-2. Pack Sizes: 50 g. Product ID: B1370-311855. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norcepharadione B
Norcepharadione B is an alkaloid isolated from Houttuynia cordata Thunb. Norcepharadione B exhibits cytotoxic activity against five human tumor cell lines (A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15) in vitro. Norcepharadione B also exhibits antimalarial activity. Group: Pharmaceutical. CAS No. 57576-41-7. Pack Sizes: 1 mg. Product ID: NP0388. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norchelerythrine
Norchelerythrine is an alkaloid isolated from Chelidonium majus that exhibits antifeeding activity. Group: Pharmaceutical. CAS No. 6900-99-8. Pack Sizes: 1 mg. Product ID: NP0709. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norepinephrine Impurities
Norepinephrine Impurities play a crucial role in the pharmaceutical industry, primarily in the quality control and characterization of norepinephrine formulations. These impurities are vital for ensuring the safety and efficacy of medications used in treating conditions like hypotension, cardiac arrest, and depression by facilitating thorough drug substance analysis and stability testing. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norethindrone Impurities
Norethindrone Impurities are crucial in the pharmaceutical industry for the quality control and assurance of norethindrone-based medications. They play a vital role in ensuring the safety and efficacy of contraceptives and hormone replacement therapies, as meticulous impurity profiling can aid in the detection of potential side effects. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Noreugenin
Noreugenin is an organic extract illuminated by its profound anti-inflammatory attributes, aiding in studying ailments spanning arthritis, asthma and inflammatory bowel disorder. Group: Pharmaceutical. CAS No. 1013-69-0. Pack Sizes: 25 mg. Product ID: NP5182. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norfloxacin-[d5]
Norfloxacin-[d5] is the labelled analogue of Norfloxacin, which is a broad-spectrum antibiotic active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase. Norfloxacin can be used to treat urinary tract infections. Group: Pharmaceutical. CAS No. 1015856-57-1. Pack Sizes: 25 mg. Product ID: BLP-012490. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norfloxacin Impurities
Norfloxacin Impurities, manifesting as byproducts during the antibiotic Norfloxacin synthesis, are essential in pharmaceutical quality control. These entities are crucial for assessing the purity and therapeutic potency of Norfloxacin, which is deployed in combating urinary, respiratory, and gastrointestinal infections, thereby guaranteeing its clinical reliability and therapeutic success. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norgestimate Impurities
Norgestimate Impurities play a critical role in the pharmaceutical industry by assisting in the quality control of norgestimate, a prominent contraceptive drug. These impurities help in identifying and quantifying unintended by-products during the drug synthesis process, ensuring the safety, efficacy, and consistency of the final pharmaceutical product. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norgestrel Impurities
Norgestrel Impurities serve as essential analytical standards within the sphere of contraceptive drug development and quality control. These impurities enable comprehensive assessment of purity and safety in norgestrel formulations, predominating in oral contraceptives and hormone replacement therapies, ensuring regulatory adherence and enhancing therapeutic effectiveness through thorough impurity profiling. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norhyoscyamine sulfate
Norhyoscyamine sulfate, a potent anticholinergic agent, exerts its therapeutic effects through the inhibition of acetylcholine activity, which makes it a valuable treatment option for several types of gastrointestinal disorders, such as motility disorders, as well as urinary incontinence. Moreover, this multifaceted medication exhibits remarkable preoperative benefits, as it can effectively reduce both respiratory and digestive secretions, underscoring its versatility and potential for widespread clinical use. Group: Pharmaceutical. CAS No. 537-29-1. Pack Sizes: 100 mg. Product ID: B1370-152647. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norisoboldine
Norisoboldine might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. Group: Pharmaceutical. CAS No. 23599-69-1. Pack Sizes: 20 mg. Product ID: B2703-464432. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(+)-Normacusine B
Tombozine is a natural alkaloid isolated from the herbs of Rauvolfia yunnanensis. Group: Pharmaceutical. CAS No. 604-99-9. Pack Sizes: 1 mg. Product ID: NP0325. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norsanguinarine
Norsanguinarine is an isoquinoline alkaloid isolated from Chelidonium majus. Norsanguinarine exhibits antimicrobial, anti-inflammatory, and anti-oxidant activities. Group: Pharmaceutical. CAS No. 522-30-5. Pack Sizes: 1 mg. Product ID: NP0710. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nortrachelogenin
Nortrachelogenin is a natural lignan found in the herbs of Trachelospermum jasminoides, it shows effects on the central nervous system producing depression in rabbits. Group: Pharmaceutical. CAS No. 34444-37-6. Pack Sizes: 1 mg. Product ID: NP4071. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Norverapamil
Norverapamil is a metabolite of Verapamil. Verapamil is a medication used for the treatment of high blood pressure, chest pain from not enough blood flow to the heart, and supraventricular tachycardia. Norverapamil is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. Uses: Calcium channel blockers. Group: Pharmaceutical. CAS No. 67018-85-3. Pack Sizes: 5 mg. Product ID: B0001-192715. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Nosiheptide
Nosiheptide is a thiopeptide antibiotic produced by Streptomyces actuosus. It has broad spectrum antibacterial activity. Group: Pharmaceutical. CAS No. 56377-79-8. Pack Sizes: 50 mg. Product ID: BBF-03904. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Notoginseng triterpenes
Notoginsenoside Fe is a natural compound isolated from the roots of Panax notoginseng. Group: Pharmaceutical. CAS No. 88105-29-7. Pack Sizes: 20 mg. Product ID: NP0062. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Notoginsenoside R1
Notoginsenoside R1 is a natural triterpenoid compound found in the roots of Panax notoginseng (Burk.)F.H.Chen. Notoginsenoside R1 exhibits antioxidant and antiapoptotic activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells. Uses: Antioxidant;antiapoptotic. Group: Pharmaceutical. CAS No. 80418-24-2. Pack Sizes: 100 mg. Product ID: BBF-05886. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Notopterol
Notopterol, coming from the roots of Notopterygium incisum, possesses the properties of cell cycle-specific inhibition and apoptosis induced. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 88206-46-6. Pack Sizes: 250 mg. Product ID: NP1110. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-p-Coumaroyloctopamine
N-p-Coumaroyloctopamine is a natural alkaloid found in the herbs of Datura arborea. Group: Pharmaceutical. CAS No. 66648-45-1. Pack Sizes: 5 mg. Product ID: NP0308. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
n-Propyl Dioxepin
N-Propyl Dioxepin, a chemical compound, has been found to hold immense potential in the field of neuroscience due to its ability to be leveraged in the creation of new pharmaceuticals that are aimed at treating a range of neurological disorders, including but not limited to Alzheimer's disease and schizophrenia. This compound has been shown to be a wonderfully proficient antagonist of the dopamine receptors, as evidenced by preclinical studies. Group: Pharmaceutical. CAS No. 4469-34-5. Pack Sizes: 10 g. Product ID: B0001-118291. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Propylmaleimide
N-Propylmaleimide. Group: Pharmaceutical. CAS No. 21746-40-7. Pack Sizes: 25 g. Product ID: B1370-309349. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Group: Pharmaceutical. CAS No. 88793-79-7. Pack Sizes: 50 mg. Product ID: BAT-010163. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-p-trans-Coumaroyltyramine
N-p-Coumaroyltyramine comes from the herbs of Exochorda racemosa. Group: Pharmaceutical. CAS No. 36417-86-4. Pack Sizes: 10 mg. Product ID: NP0406. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide, an intriguing chemical substance, has garnered interest in the biomedical domain as a plausible remedy for assorted cancer types. This compound exerts its therapeutic effects by curbing certain enzymes and provoking apoptosis in malignant cells, thereby causing their demise. Although promising, further scientific investigations and clinical deliberations are fundamental to ascertain its potency and risk profiles. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: B0001-254048. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NS-304
NS-304 is a selective prostacyclin IP1 receptor agonist as prodrug of the active form of MRE-269 with a Ki value of 20 nM. Uses: Antihypertensive agents. Group: Pharmaceutical. CAS No. 475086-01-2. Pack Sizes: 5 g. Product ID: B2693-313936. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NSC 23005 sodium
NSC23005 sodium is a p18INK inhibitor. It can promote hematopoietic stem cell expansion with ED50 of 5.21 nM. Group: Pharmaceutical. CAS No. 1796596-46-7. Pack Sizes: 100 mg. Product ID: B2693-169415. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NSC 23766 trihydrochloride
NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as well as the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells. Group: Pharmaceutical. CAS No. 1177865-17-6. Pack Sizes: 25 mg. Product ID: B0084-007260. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NSI-189
NSI-189 is an experimental drug being studied by Neuralstem, Inc. Research into NSI-189 has been funded by the Defense Advanced Research Projects Agency (DARPA) and the National Institutes of Health (NIH) for the treatment of major depressive disorder. NSI-189 successfully completed a phase 1 clinical trial in 2011 where it was administered to 41 healthy volunteers. A phase 1b clinical trial for treating major depressive disorder in 24 patients started in 2012 and completed in July 2014. The study suggests that there were improvements in the patients' condition when the doses were 40/80 mg per day, but no significant improvements were seen for a higher dosage of 120 mg/day. Neuralstem intends to pursue further clinical trials for a variety of neurological conditions, including major depressive disorder, traumatic brain injury, Alzheimer's disease, post-traumatic stress disorder, stroke, and natural cognitive and memory decline in aging. Uses: For research used only. Group: Pharmaceutical. CAS No. 1270138-40-3. Pack Sizes: 5 g. Product ID: B0084-462290. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-SMP
N-SMP is a potent synthetic compound known for its efficacy against various neurological disorders. As a powerful inhibitor, this compound specifically targets key enzymes involved in the progression of these debilitating diseases. In addition, N-SMP is also widely used as a linker for antibody-drug conjugation. Group: Pharmaceutical. CAS No. 55750-61-3. Pack Sizes: 5 g. Product ID: BAT-006479. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NSP-DMAE-NHS
NSP-DMAE-NHS is an acridinium ester chemiluminescent reagent containing N-sulfopropyl groups. It is useful in the clinical diagnostic industry especially in automated immunochemical analyzers such as Siemens Healthcare Diagnostics' ADVIA Centaur systems. Group: Pharmaceutical. CAS No. 194357-64-7. Pack Sizes: 5 mg. Product ID: B0245-172748. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NSP-SA-NHS
It is a direct chemiluminescent reagent, used to mark proteins, antigens, antibodies, nucleic acids (DNA, RNA), etc. Group: Pharmaceutical. CAS No. 199293-83-9. Pack Sizes: 5 mg. Product ID: B0001-173202. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Succinimidyl 3-maleimidopropionate
BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Pharmaceutical. CAS No. 55750-62-4. Pack Sizes: 25 g. Product ID: BAT-006473. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Tert-Butyldibenzylamine
An impurity of Terbutaline. Terbutaline is a fast-acting bronchodilator as well as a β2 adrenergic receptor agonist used to treat asthma and premature labor. Group: Pharmaceutical. CAS No. 30923-82-1. Pack Sizes: 10 mg. Product ID: B2694-106576. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-tert-Butylglycine Acid Chloride HCl
N-tert-Butylglycine Acid Chloride HCl (CAS# 915725-52-9 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 915725-52-9. Pack Sizes: 50 mg. Product ID: B2699-100530. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
Block Copolymer Synthesis Using a Commercially Available NMP Inititator. Group: Pharmaceutical. CAS No. 227000-59-1. Pack Sizes: 2 g. Product ID: B2699-187954. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Tetradecylpropane-1,3-diamine
N-Tetradecylpropane-1,3-diamine is a useful research chemical. Group: Pharmaceutical. CAS No. 4317-79-7. Pack Sizes: 1 g. Product ID: B1370-068758. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Tosyl-L-alanyloxyindole
N-Tosyl-L-alanyloxyindole. Group: Pharmaceutical. CAS No. 75062-54-3. Pack Sizes: 2.5 g. Product ID: BAT-007721. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-trans-Feruloyl-3-methoxytyramine
N-Feruloyl-3-methoxytyramine is extracted from the roots of Litsea hypophaea. Group: Pharmaceutical. CAS No. 78510-19-7. Pack Sizes: 1 mg. Product ID: NP0348. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
N-Trans-Feruloyltyramine
N-trans-Feruloyltyramine(NTF) ,a natural plant phenylpropanoid which is isolated from the herbs of Cannabis sativa L. exhibits the activity of anti-oxidative and has hepatoprotective effect. N-trans-Feruloyltyramine is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor. Uses: Anti-oxidative. Group: Pharmaceutical. CAS No. 66648-43-9. Pack Sizes: 10 mg. Product ID: NP0183. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
NU7441
NU7441 is a highly potent and selective DNA-PK inhibitor (IC50=14 nM), exhibiting ATP-competitive inhibition kinetics. NU7441 increased the cytotoxicity of ionizing radiation and etoposide in SW620, LoVo, and V3-YAC cells but not in V3 cells, confirming that potentiation was due to DNA-PK inhibition. NU7441 substantially retarded the repair of ionizing radiation-induced and etoposide-induced DSB. NU7441 appreciably increased G(2)-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. In mice bearing SW620 xenografts, NU7441 concentrations in the tumor necessary for chemopotentiation in vitro were maintained for at least 4 hours at nontoxic doses. NU7441 increased etoposide-induced tumor growth delay 2-fold without exacerbating etoposide toxicity to unacceptable levels. In conclusion, NU7441 shows sufficient proof of principle through in vitro and in vivo chemosensitization and radiosensitization to justify further development of DNA-PK inhibitors for clinical use. Group: Pharmaceutical. CAS No. 503468-95-9. Pack Sizes: 100 mg. Product ID: B1370-194516. Molecular formula: Custom synthesis is available. Send your inquiries for more information.