Activated Carbon UK Suppliers, Bulk Distributors & Wholesalers
Where to buy Activated Carbon in the United Kingdom in the UK
We have compiled a list of Activated Carbon suppliers in the UK. Activated carbon, also called activated charcoal, activated coal, or carbo activatus.
Looking for a particular Activated Carbon to purchase
Simply use the search box, then use the suppliers website link to enquire or for prices. The companies listed that supply activated carbon for sale have a genuine UK presence and include: distributors, wholesalers, industrial, retail and bulk suppliers.
| Product | Description | |
|---|---|---|
| 2-(2-(2-Aminoethoxy)ethoxy)acetic acid | H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs. Group: Pharmaceutical. Alternative Names: Amino-PEG2-CH2CO2H; Amino-PEG2-CH2COOH; Amino-PEG2-acetic acid. CAS No. 134978-97-5. Pack Sizes: 1 g. Product ID: BAT-006212. Molecular formula: C6H13NO4. Mole weight: 163.17. Custom synthesis is available. Send your inquiries for more information. |  London |
| AbK | AbK is an unnatural amino acid and is genetically encoded for site-selective incorporation into proteins in mammalian cells and bacteria. It has efficient photocrosslinking in vitro and in vivo. It is used as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUA pairs. Group: Pharmaceutical. Alternative Names: N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine. CAS No. 1253643-88-7. Pack Sizes: 1mg;1g;10g. Product ID: 1253643-88-7. Molecular formula: C13H21N4O6F3. Mole weight: 272.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Boc-D-FMK | BOC-D-FMK is a cell-permeable broad-spectrum caspase inhibitor that fully inhibits the pro-apoptotic effect of tumor necrosis factor-α (TNFα). It has been found to reduce the activation of nuclear factor kappa light chain enhancer of activated B cells (NF-kB), suppress the phosphorylation of subunit nuclear factor kappa light polypeptide gene enhancer in B cells inhibitor α (IkBα) and inhibit TNF-induced expression of intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1). Moreover, it has also effectively attenuated the hepatocyte apoptosis in bile duct-ligated rats potentially improving the survival rates. Uses: Caspase inhibitors. Group: Pharmaceutical. Alternative Names: Boc-Asp(OMe)-fluoromethyl ketone; Caspase Inhibitor 3; N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone; BAF; Boc-D-Fluoromethyl Ketone; Boc-D(OMe)-FMK; 3S-[[(1,1-dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-pentanoic acid, methyl ester; Caspase Inhibitor III. CAS No. 187389-53-3. Pack Sizes: 100 mg. Product ID: BAT-010386. Molecular formula: C11H18FNO5. Mole weight: 263.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Olaparib | Olaparib, also known as AZD-2281 or KU-59436, is a small-molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks; PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks. Group: Pharmaceutical. Alternative Names: AZD2281; AZD-2281; AZD 2281; KU59436; KU-59436; KU 59436; KU0059436; KU-0059436; KU 0059436; Olaparib. trade name Lynparza; 4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one. CAS No. 763113-22-0. Pack Sizes: 1 g. Product ID: B0084-076683. Molecular formula: C24H23FN4O3. Mole weight: 434.471. Custom synthesis is available. Send your inquiries for more information. | London |
| PAR4 (1-6) (human) | PAR4 (1-6) is a synthetic hexapeptide agonist of proteinase-activated receptor 4 (PAR4). PAR4 is a thrombin receptor activated by platelet, and acts as a modulator of cellular responses that serve as hallmarks of inflammation. Group: Pharmaceutical. Alternative Names: H-Gly-Tyr-Pro-Gly-Gln-Val-OH; (2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-1-[(2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid. CAS No. 225779-44-2. Pack Sizes: 25 mg. Product ID: BAT-006098. Molecular formula: C28H41N7O9. Mole weight: 619.67. Custom synthesis is available. Send your inquiries for more information. | London |
| 4'-Bromo-4-cyanobiphenyl | 4'-Bromo-4-cyanobiphenyl is a biologically active agent that serves as a crucial constituent in the synthesis of medicinal drugs utilized in the remedy of different ailments, including cancer, autoimmune disorders, and arthritis. Its versatile chemical properties allow for enhanced efficacy in drug development, making it a valuable pharmaceutical intermediate. Group: Pharmaceutical. Alternative Names: 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile. CAS No. 57774-35-3. Pack Sizes: 25 g. Product ID: B2699-249367. Molecular formula: C13H8BrN. Mole weight: 258.11. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Epi Lincomycin Hydrochloride Salt | 7-Epi Lincomycin Hydrochloride Salt is an epimer of Lincomycin, a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. It is less potent bactericidal than its (7R)-epimer. Group: Pharmaceutical. Alternative Names: Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1- thio-L-threo-α-D-galacto-octopyranoside Hydrochloride; trans-α-Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)- 1-thio-L-threo-D-galacto-octopyranoside. CAS No. 26389-84-4. Pack Sizes: 5 mg. Product ID: B2694-472409. Molecular formula: C18H35ClN2O6S. Mole weight: 443. Custom synthesis is available. Send your inquiries for more information. | London |
| A-769662 | A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM in cell-free assays, little effect on GPPase/FBPase activity. Group: Pharmaceutical. Alternative Names: 4-Hydroxy-3-(2'-hydroxy-[1,1'-biphenyl]-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile. CAS No. 844499-71-4. Pack Sizes: 1mg;1g;10g. Product ID: 844499-71-4. Molecular formula: C20H12N2O3S. Mole weight: 360.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Active Carbon | 1kg Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials. Formula: C. CAS No. 7440-44-0. Prepack ID : 90021896-1kg. Molecular Weight : 12.01. |  |
| Active Carbon (Granulate 1-2 mm) | 100g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C. CAS No. 7440-44-0. Prepack ID : 90025254-100g. Molecular Weight : 12.01. | |
| AEEA-AEEA | 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic acid is a complex organic molecule characterized by multiple functional groups and heteroatoms within its structure. It contains an amino group (-NH2) at the 17th position, a ketone group (oxo) at the 10th position, and several ether linkages (tetraoxa) throughout its carbon chain. Additionally, it features an amide linkage (aza) at the 9th position, which integrates nitrogen into the backbone. This compound is significant in biochemical and pharmaceutical research due to its potential applications in the design and synthesis of novel molecules with specific biological activities. Group: Pharmaceutical. Alternative Names: 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic acid; 8-Amino-3,6-dioxaoctanoic acid dimer; 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid; H-Adoa-Adoa-OH; H2N-PEG2-NH-PEG2-CH2COOH. CAS No. 1143516-05-5. Pack Sizes: 1 g. Product ID: BAT-016487. Molecular formula: C12H24N2O7. Mole weight: 308.33. Custom synthesis is available. Send your inquiries for more information. | London |
| Aglain C | Aglain C, an organic alkaloid of natural origins, demonstrates anti-tumor activity, thus possessing potential application in diverse cancer treatment modalities. It elicits apoptosis, or cell death, in malignant cells, and exhibits anti-inflammatory properties. To ascertain its therapeutic value comprehensively, additional examination is warranted. Group: Pharmaceutical. Alternative Names: N-((S)-1-((2R,3S,4R,5R,10S)-5,10-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-3-phenyl-2,3,4,5-tetrahydro-2,5-methanobenzo[b]oxepine-4-carbonyl)pyrrolidin-2-yl)-2-methylbutanamide. CAS No. 177468-85-8. Pack Sizes: 2 mg. Product ID: NP0163. Molecular formula: C36H42N2O8. Mole weight: 630.727. Custom synthesis is available. Send your inquiries for more information. | London |
| Amarogentin | Amarogentin exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways and displays immunomodulatory effects in human mast cells and keratinocytes. It inhibits the growth of SNU-16 human gastric cancer cells (IC50 = 12.4 μM) and increases apoptosis when used at a concentration of 50 μM. Amarogentin dose-dependently reduces tumor growth in a SNU-16 nude mouse xenograft model. Amarogentin may offer therapeutic potential for preventing or treating thromboembolic disorders, it prevents platelet activation through the inhibition of PLC γ2-PKC cascade and MAPK pathway. Group: Pharmaceutical. Alternative Names: sweroside-2'-(3'',5'',3'''-trihydroxydiphenyl)-2''-carboxylic acid ester; (4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one. CAS No. 21018-84-8. Pack Sizes: 50 mg. Product ID: B1370-062768. Molecular formula: C29H30O13. Mole weight: 586.54. Custom synthesis is available. Send your inquiries for more information. | London |
| AMI-1 | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Group: Pharmaceutical. Alternative Names: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. CAS No. 20324-87-2. Pack Sizes: 50 mg. Product ID: B2693-087022. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. Custom synthesis is available. Send your inquiries for | London |
| Apimostinel | Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Group: Pharmaceutical. Alternative Names: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel;(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. CAS No. 1421866-48-9. Pack Sizes: 5 mg. Product ID: B2693-475419. Molecular formula: C25H37N5O6. Mole weight: 503.6. Custom synthesis is available. Send your inquiries for more information. | London |
| ASP-9521 | ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). ASP9521 has demonstrated anti-tumour activity in in vitro and in vivo preclinical models. ASP9521 inhibited conversion of androstenedione (AD) into testosterone (T) by recombinant human or cynomolgus monkey AKR1C3 in a concentration-dependent manner. Group: Pharmaceutical. Alternative Names: ASP9521; ASP-9521; ASP 9521. AKR1C3 inhibitor ; 17HSD5 inhibitor;4-(2-Hydroxy-2-methylpropyl)piperidino(5-methoxy-1H-indole-2-yl)methanone; 1-[1-[(5-Methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl]-2-methylpropan-2-ol. CAS No. 1126084-37-4. Pack Sizes: 100 mg. Product ID: B0084-462669. Molecular formula: C19H26N2O3. Mole weight: 330.428. Custom synthesis is available. Send your inquiries for more information. | London |
| Bacitracin B1 (acetate) | It is produced by the strain of Bacillus sp. It is a highly purified form of bacitracin B1 and a compound present in standard grade bacitracin. It together with bacitracin B2 is slightly less active than bacitracin A. Group: Pharmaceutical. Alternative Names: Bacitracin F, 1-[N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucine]-6-L-valine-; Bacitracin B1a; L-Asparagine, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-a-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-valyl-D-phenylalanyl-L-histidyl-D-a-aspartyl-, cyclic (10,4)-peptide, [4R-[2(1S*,2S*),4R*]]-. CAS No. 57762-79-5. Pack Sizes: 10 mg. Product ID: BBF-04325. Molecular formula: C65H101N17O16S. Mole weight: 1408.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Boc-LRR-AMC (trifluoroacetate salt) | Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Group: Pharmaceutical. Alternative Names: Boc-Leu-Arg-Arg-AMC.TFA; N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, trifluoroacetate salt. Pack Sizes: 50 mg. Product ID: BAT-016477. Molecular formula: C35H53F3N10O9. Mole weight: 814.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Capecitabine impurity D | A Capecitabine analog which shows antitumor activity. Group: Pharmaceutical. Alternative Names: 5'-Deoxy-5-fluoro-N4-[(2-methylbutoxy)carbonyl]cytidine; 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine; Capecitabine EP Impurity D; 2-Methylbutyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; 5'-Deoxy-5-fluoro-N4-(2-methyl-1-butyloxycarbonyl)cytidine. CAS No. 910129-15-6. Pack Sizes: 25 mg. Product ID: B0246-468068. Molecular formula: C15H22FN3O6. Mole weight: 359.35. Custom synthesis is available. Send your inquiries for more information. | London |
| CDDO Imidazolide | CDDO Imidozolide is a synthetic triterpenoid as a Nrf2 signaling activator with highly active in suppressing cellular proliferation of human leukemia and breast cancer cell. Uses: Nrf2 signaling activator. Group: Pharmaceutical. Alternative Names: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; (4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile. CAS No. 443104-02-7. Pack Sizes: 10 mg. Product ID: B2693-474173. Molecular formula: C34H43N3O3. Mole weight: 541.72. Custom synthesis is available. Send your inquiries for more information. | London |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Group: Pharmaceutical. Alternative Names: CGI1746; CGI-1746; CGI 1746. 4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. CAS No. 910232-84-7. Pack Sizes: 100 mg. Product ID: B0084-430556. Molecular formula: C34H37N5O4. Mole weight: 579.69. Custom synthesis is available. Send your inquiries for more information. | London |
| CHIR-090 | CHIR-090 is a very potent and tight-binding inhibitor of LpxC, which is a zinc-dependent amidase and present in almost all Gram-negative bacteria, and is a promising target for the development of novel antibiotic substances against multigrug-resistant Gram-negative bacteria. Its Ki value is 4.0 nM. It displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. It has a different selectivity with the reported LpxC inhibitor L-161. It has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli by inhibiting LpxC orthologs at low nM concentrations. It is an excellent lead for the further development of new antibiotics targeting the lipid A pathway. Uses: Chir-090 displays two-step time-dependent inhibition and kills a wide range of gram-negative pathogens as effectively as ciprofloxacin or tobramycin. it has excellent antibiotic activity against pseudomonas aeruginosa and escherichia coli by inhibiting lpxc orthologs at low nm concentrations. Group: Pharmaceutical. Alternative Names: CHIR-090; CHIR 090; CHIR090. N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide. CAS No. 728865-23-4. Pack Sizes: 300 mg. Product ID: B0084-474822. Molecular formula: C24H27N3O5. Mole weight: 437.49. Custom synthesis is available. Send your inquiries for more information. | London |
| CHIR-99021 | CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES). Uses: Potential antineoplastic agent. Group: Pharmaceutical. Alternative Names: CHIR-99021; CT99021; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile. CAS No. 252917-06-9. Pack Sizes: 100 mg. Product ID: B0084-462893. Molecular formula: C22H18Cl2N8. Mole weight: 465.342. Custom synthesis is available. Send your inquiries for more information. | London |
| Cilastatin Ammonium Salt | Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Group: Pharmaceutical. Alternative Names: (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Ammonium Salt; MK-791 Ammonium Salt. CAS No. 877674-82-3. Pack Sizes: 500 mg. Product ID: B2693-468925. Molecular formula: C16H29N3O5S. Mole weight: 375.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Cilastatin sodium | Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Group: Pharmaceutical. Alternative Names: L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)?-7-[[(2R)?-2-Amino-2-carboxyethyl]?thio]?-2-[[[(1S)?-2,?2-dimethylcyclopropyl]?carbonyl]?amino]?-2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate. CAS No. 81129-83-1. Pack Sizes: 1 g. Product ID: B0084-077802. Molecular formula: C16H25N2NaO5S. Mole weight: 380.43. Custom synthesis is available. Send your inquiries for more information. | London |
| CORM-3 | CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. It attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. Group: Pharmaceutical. Alternative Names: Tricarbonylchloro(glycinato)ruthenium; (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium; CORM3; CORM 3. CAS No. 475473-26-8. Pack Sizes: 50 mg. Product ID: B0084-463459. Molecular formula: C5H4ClNO5Ru. Mole weight: 294.61. Custom synthesis is available. Send your inquiries for more information. | London |
| CUDA | CUDA is an inhibitor of soluble epoxide hydrolase (sEH) which catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids (DiHETrEs; DHETs) thereby diminishing their activity with IC50 values of 11.1 nM and 112 nM for the mouse and human enzymes, respectively. Group: Pharmaceutical. Alternative Names: 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid. CAS No. 479413-68-8. Pack Sizes: 25 mg. Product ID: B2693-251168. Molecular formula: C19H36N2O3. Mole weight: 340.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Dabigatran etexilate mesylate | Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. It is a reversible and selective, direct thrombin inhibitor (DTI). Group: Pharmaceutical. Alternative Names: Ethyl 3-(((2-(((4-(((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-1h-benzimidazol-5-yl)carbonyl)(pyridin-2-yl)amino)propanoate, methanesulfonate; Dabigatran etexilate mesylate; BIBR 1048MS; BIBR1048MS; BIBR-1048MS; BIBR 1048; BIBR1048; BIBR-1048; band name: Pradaxa. CAS No. 872728-81-9. Pack Sizes: 2 g. Product ID: B0084-461975. Molecular formula: C35H45N7O8S. Mole weight: 723.84. Custom synthesis is available. Send your inquiries for more information. | London |
| DUPA(OtBu)-OH | DUPA(OtBu)-OH is a PEG linker for antibody-drug-conjugation (ADC). DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. Group: Pharmaceutical. Alternative Names: (S)-5-tert-Butoxy-4-(3-((s)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic Acid; L-Glutamic acid, N-[[[(1S)-3-carboxy-1-[(1,1-dimethylethoxy)carbonyl]propyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester; 2-[3-(1,3-bis-tert-butoxycarbonylpropyl)ureido]pentanedioic acid 1-tert-butyl ester. CAS No. 1026987-94-9. Pack Sizes: 500 mg. Product ID: BADC-00511. Molecular formula: C23H40N2O9. Mole weight: 488.57. Custom synthesis is available. Send your inquiries for more information. | London |
| E7046 | E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities. Group: Pharmaceutical. Alternative Names: E7046; E-7046; E 7046. 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid. CAS No. 1369489-71-3. Pack Sizes: 50 mg. Product ID: B0084-007670. Molecular formula: C22H18F5N3O4. Mole weight: 483.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Edoxaban Tosylate Hydrate | In human plasma, Edoxaban doubles prothrombin time and activates partial thromboplastin time at 0.256 and 0.508 μM, respectively. Group: Pharmaceutical. Alternative Names: N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-Toluenesulfonate hydrate; N-(5-Chloropyridin-2-yl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide mono(p-toluenesulfonate) hydrate; Edoxaban p-toluenesulfonate monohydrate. CAS No. 1229194-11-9. Pack Sizes: 1 g. Product ID: B0084-463378. Molecular formula: C24H30ClN7O4S.C7H8O3S.H2O. Mole weight: 738.27. Custom synthesis is available. Send your inquiries for more information. | London |
| ESI-08 | ESI-08 is a potent and selective EPAC antagonist that completely inhibits both EPAC1 and EPAC2 activity (IC50 = 8.4 μM for EPAC2) without inhibition of cAMP-mediated PKA activation. Group: Pharmaceutical. Alternative Names: HJC-1-65; 4-Cyclohexyl-2-(2,5-dimethylbenzylthio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile. CAS No. 301177-43-5. Pack Sizes: 50 mg. Product ID: B1370-379925. Molecular formula: C20H23N3OS. Mole weight: 353.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Fmoc-Dha-OH | Fmoc-Dha-OH, a pivotal intermediate, is used for synthesizing a plethora of biologically active compounds encompassing antimicrobial peptides, dipeptidyl peptidase IV inhibitors, and enzyme inhibitors. Researchers have employed it to fabricate Fmoc-Dha-OH-derived peptidomimetics manifested by the impeding activity against a myriad of cancer cell lines. The said compound holds sheer potential for the design and development of novel pharmaceutical agents targeting numerous diseases. Group: Pharmaceutical. Alternative Names: Fmoc-dehydro-Ala-OH; N-(9H-Fluorene-9-ylmethoxycarbonyl)-2,3-didehydro-L-alanine; 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)acrylic acid. CAS No. 261522-33-2. Pack Sizes: 500 mg. Product ID: BAT-008269. Molecular formula: C18H15NO4. Mole weight: 309.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Fmoc-Leu-OH | Fmoc-Leu-OH is an amino acid derivative. It is also one of the novel PPARγ ligands that can reduce osteoclasts differentiation through activating PPARγ. Group: Pharmaceutical. Alternative Names: Fmoc-L-Leu-OH; N-(9-fluorenylmethoxycarbonyl)-L-leucine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine; NPC 15199; NPC15199; NPC-15199. CAS No. 35661-60-0. Pack Sizes: 1 kg. Product ID: BAT-008101. Molecular formula: C21H23NO4. Mole weight: 353.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Fmoc-N-Me-Dab(Boc)-OH | Fmoc-N-Me-Dab(Boc)-OH, a peptide derivative, finds extensive applications in the pharmaceutical and biologically active compound synthesis arena. One can leverage it as a fundamental building block to engineer peptide-based drugs with proven anti-tumor activity. The versatility of Fmoc-N-Me-Dab(Boc)-OH renders it an indispensable tool in the scientific community, and its intricate molecular structure continues to inspire novel applications in the field of drug discovery and development. Group: Pharmaceutical. Alternative Names: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic acid. CAS No. 2044702-38-5. Pack Sizes: 100 mg. Product ID: BAT-008506. Molecular formula: C25H30N2O6. Mole weight: 454.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Meropenem Trihydrate | Meropenem Trihydrate is a carbapenem antibiotic, which has broad spectrum antibacterial activity. Group: Pharmaceutical. Alternative Names: [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-3-[[5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Trihydrate; (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Trihydrate; SM-7338. CAS No. 119478-56-7. Pack Sizes: 100 mg. Product ID: BBF-04632. Molecular formula: C17H25N3O5S.3H2O. Mole weight: 437.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl 5-Acetamido-7,8,9-tri-O-acetyl-5-N,4-O-carbonyl-3,5-dideoxy-2-S-phenyl-2-thio-D-glycero-b-D-galacto-2-nonulopyranosylonate | Methyl 5-Acetamido-7,8,9-tri-O-acetyl-5-N,4-O-carbonyl-3,5-dideoxy-2-S-phenyl-2-thio-D-glycero-b-D-galacto-2-nonulopyranosylonate, a chemical entity of paramount importance in pharmaceutical studies. This compound plays a key role in antiviral drug development, primarily focusing on HIV reverse transcriptase and integrase. Moreover, it exhibits inhibitory activity against an array of viruses, including Ebola and Zika, which presents a profound scope for therapeutic interventions. Group: Pharmaceutical. Alternative Names: Methyl (Phenyl 5-Acetamido-7,8,9-tri-O-acetyl-5-N,4-O-carbonyl-3,5-dideoxy-2-thio-D-glycero-b-D-galacto-2-nonulopyranosid)onate. CAS No. 934591-76-1. Pack Sizes: 250 mg. Product ID: B2705-001798. Molecular formula: C25H29NO12S. Mole weight: 567.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Mono-methyl terephthalate | Mono-methyl terephthalate is used in the synthesis of Hepatits C antiviral activity. Also used in the design and preparation of benzamide derivatives as BRAFV600E inhibitors, which if mutated, can influence malignancies and melanomas. Uses: Mono-methyl terephthalate is used in the synthesis of hepatits c antiviral activity. also used in the design and preparation of benzamide derivatives as brafv600e inhibitors, which if mutated, can influence malignancies and melanomas. Group: Pharmaceutical. Alternative Names: MMT; 1,4-Benzenedicarboxylic Acid Monomethyl Ester; Terephthalic Acid Monomethyl Ester; 4-(Carbomethoxy)benzoic Acid; 4-(Methoxycarbonyl)benzoic Acid; 4-[(Methyloxy)carbonyl]benzoic Acid; Hydrogen Methyl Terephthalate; Methyl 4-Carboxybenzoate; Methyl Hydrogen Terephthalate; Methyl p-Carboxybenzoate; Methyl p-Phthalate; Monomethyl terephthalate; NSC 210838; p-(Methoxycarbonyl)benzoic Acid; p-Carbomethoxybenzoic Acid. CAS No. 1679-64-7. Pack Sizes: 1mg;1g;10g. Product ID: BAT-006428. Molecular formula: C9H8O4. Mole weight: 180.16. Custom synthesis is available. Send your inquiries for more information. | London |
| Motolimod | Motolimod is a small-molecule agonist of TLR8, with potential immunostimulating and antineoplastic activities. Group: Pharmaceutical. Alternative Names: VTX-2337; VTX 2337; VTX2337; Motolimod; 2-amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide. CAS No. 926927-61-9. Pack Sizes: 100 mg. Product ID: B0084-462238. Molecular formula: C28H34N4O2. Mole weight: 458.6. Custom synthesis is available. Send your inquiries for more information. | London |
| N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-2-naphthalenesulfonamide | N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-2-naphthalenesulfonamide, a profound small molecule inhibitor designed to target Cancerous Enzyme Carbonic Anhydrase IX (CAIX). This molecule is capable of exhibiting its potential therapeutic efficacy against various malignancies in numerous body sites including Breast, Prostate, and Kidney. This inhibitor is highly recommended due to its ability to repress the CAIX activity, a pivotal catalyst responsible for tumor inception, advancement, and invasion, rendering it a glimmer of hope as a Cancer treatment. Group: Pharmaceutical. Alternative Names: oxobenzoxazinyl naphthalene sulfoanilide; 2-Naphthalenesulfonamide, N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-. CAS No. 10128-55-9. Pack Sizes: 250 mg. Product ID: B2699-013690. Molecular formula: C24H16N2O4S. Mole weight: 428.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Neratinib | Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Group: Pharmaceutical. Alternative Names: 2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide; (E)-N-[4-[[3-Chloro-4-((pyridin-2-yl)meth. CAS No. 698387-09-6. Pack Sizes: 500 mg. Product ID: B0084-347125. Molecular formula: C30H29ClN6O3. Mole weight: 557.04. Custom synthesis is available. Send your inquiries for more information. | London |
| Nutlin-3b | Nutlin-3b, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM. Group: Pharmaceutical. Alternative Names: Nutlin-3; nutlin 3; Nutlin 3b; FJA1772CVW; (+)-Nutlin-3; CHEMBL2152332; CHEBI:46742; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one; 2-Piperazinone, 4-(((4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl)-1H-imidazol-1-yl)carbonyl)-; 4-((4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one; 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone; cis-4-{[4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazol-1-yl]carbonyl}piperazin-2-one. CAS No. 675576-97-3. Pack Sizes: 100 mg. Product ID: B2693-459422. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Olcegepant | Olcegepant is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide (CGRP) receptor, primarily explored for the prevention of migraines in adults. CGRP is a neuropeptide that plays a significant role in migraine pathophysiology, and its receptors are found in the trigeminal ganglion and the central nervous system. By blocking the CGRP receptor, olcegepant aims to prevent the activation of pain pathways associated with migraines. Group: Pharmaceutical. Alternative Names: BIBN-4096; BIBN4096; BIBN 4096; BIBN-4096BS; BIBN4096BS; BIBN 4096BS; N-((R)-1-(((S)-6-Amino-1-oxo-1-(4-(pyridin-4-yl)piperazin-1-yl)hexan-2-yl)amino)-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl)-4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carboxamide; 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-piperazine. CAS No. 204697-65-4. Pack Sizes: 10 mg. Product ID: B0084-441440. Molecular formula: C38H47Br2N9O5. Mole weight: 869.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Pirlimycin | A semi-synthetic lincosamide prepared from clindamycin by hydrolysing the propyl N-methylproline and re-annealing a 4-ethylpipecolic acid. It is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans by binding to the 23S ribosomal subunit, blocking protein synthesis. Group: Pharmaceutical. Alternative Names: U-57930E; methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-2-piperidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside. CAS No. 79548-73-5. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03947. Molecular formula: C17H31ClN2O5S. Mole weight: 410.96. Custom synthesis is available. Send your inquiries for more information. | London |
| PKR-IN-1 | Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it is hypothesized that PKM2 is a potential target for cancer therapy. Modulation of PKM2 might also be effective in the treatment of obesity, diabetes, autoimmune conditions, and antiproliferation-dependent diseases. Group: Pharmaceutical. Alternative Names: Mitapivat; AG-348; N-(4-((4-(Cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-8-quinolinesulfonamide. CAS No. 1260075-17-9. Pack Sizes: 100 mg. Product ID: B0084-463157. Molecular formula: C24H26N4O3S. Mole weight: 450.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Punicalin | Punicalin is an ellagitannin. It is a highly active carbonic anhydrase inhibitor with strong antioxidative activity. Punicalin have anti-hepatotoxic activity but the larger dose of punicalin induced liver damage. Group: Pharmaceutical. Alternative Names: D-Glucose, cyclic 4,6-[(2S,2'S)-2,2'-(5,10-dihydro-2,3,7,8-tetrahydroxy-5,10-dioxo[1]benzopyrano[5,4,3-cde][1]benzopyran-1,6-diyl)bis[3,4,5-trihydroxybenzoate]]; 2,20,1,23-(Epoxy[2]propene[1,2]diyl[3]ylidene)-11H,15H-tribenzo[g,i,q][1,5,12]trioxacyclononadecin, D-glucose deriv.; [1]Benzopyrano[5,4,3-cde][1]benzopyran, D-glucose deriv. CAS No. 65995-64-4. Pack Sizes: 20 mg. Product ID: B1370-465409. Molecular formula: C34H22O22. Mole weight: 782.53. Custom synthesis is available. Send your inquiries for more information. | London |
| (R)-Citalopram Oxalate | (R)-Citalopram Oxalate is an inhibitor of serotonin (5-HT) uptake. It shows antidepressant activity. Group: Pharmaceutical. Alternative Names: 1-(3-Dimethylaminopropyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile Oxalate. CAS No. 219861-53-7. Pack Sizes: 25 mg. Product ID: B0211-469040. Molecular formula: C22H23FN2O5. Mole weight: 414.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Regorafenib | Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. Uses: Antineoplastic agent. Group: Pharmaceutical. Alternative Names: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506. CAS No. 755037-03-7. Pack Sizes: 500 mg. Product ID: BBF-05856. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83. Custom synthesis is available. Send your inquiries for more information. | London |
| Regorafenib Impurity 6 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Group: Pharmaceutical. Alternative Names: Regorafenib Impurity 6; Regorafenib metabolite M6; 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic acid; ZU2HG2Y956; UNII-ZU2HG2Y956; 2-Pyridinecarboxylic acid, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)-3-fluorophenoxy)-; 4-(4-((4-Chloro-3-(trifluoromethyl)phenyl)carbamoylamino)-3-fluoro-phenoxy)pyridine-2-carboxylic acid; 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]pyridine-2-carboxylic acid; SCHEMBL4609009; 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy) picolinic acid. CAS No. 1187945-05-6. Pack Sizes: 50 mg. Product ID: B2694-483711. Molecular formula: C20H12ClF4N3O4. Mole weight: 469.78. Custom synthesis is available. Send your inquiries for more information. | London |
| Regorafenib N-Oxide (M2 Metabolite) | A metabolite of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Group: Pharmaceutical. Alternative Names: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 1-Oxide. CAS No. 835621-11-9. Pack Sizes: 25 mg. Product ID: B2694-483714. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.82. Custom synthesis is available. Send your inquiries for more information. | London |
| Rezafungin | Rezafungin, a next-generation, broad-spectrum and long-lasting echinocandin, has potent antifungal activity against Candida spp., Aspergillus spp. and Pneumocystis spp. Group: Pharmaceutical. Alternative Names: Biafungin; CD101; SP-3025; 2-{[(2R,6S,9S,11R,12S,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-Dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxo-9-({[4''-(pentyloxy)-1,1':4',1''-terphenyl-4-yl]carbonyl}amino)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl]oxy}-N,N,N-trimethylethanaminium. CAS No. 1396640-59-7. Pack Sizes: 10 mg. Product ID: BBF-05702. Molecular formula: C63H85N8O17+. Mole weight: 1226.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Seco-DUBA | seco-DUBA hydrochloride is a cell-permeable pro-drug that is cleaved into the active toxin (DUBA) in intracellular lysosomes by proteases, after internalization. The payload then alkylates the DNA, causing DNA damage and cell death. Group: Pharmaceutical. Alternative Names: Seco-duocarmycin; (S)-N-(2-(9-chloro-1-ethyl-5-hydroxy-2,3-dihydro-1H-benzo[e]indole-3-carbonyl)imidazo[1,2-a]pyridin-6-yl)-4-hydroxybenzamide; Benzamide, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-9-methyl-3H-benz[e]indol-3-yl]carbonyl]imidazo[1,2-a]pyridin-6-yl]-4-hydroxy-; N-[2-[[(1S)-1-(Chloromethyl)-1,2-dihydro-5-hydroxy-9-methyl-3H-benz[e]indol-3-yl]carbonyl]imidazo[1,2-a]pyridin-6-yl]-4-hydroxybenzamide. CAS No. 1227961-59-2. Pack Sizes: 1 mg. Product ID: BADC-01400. Molecular formula: C29H23ClN4O4. Mole weight: 526.97. Custom synthesis is available. Send your inquiries for more information. | London |
| Sulfometuron methyl | Sulfometuron methyl acts as an acetolactate synthase inhibitor, a herbicide, and an active antibacterial agent. Sulfometuron methyl is a substituted pyrimide compound for proteomics research. Group: Pharmaceutical. Alternative Names: Benzoic acid, 2-[[[[(4,6-dimethyl-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-, methyl ester; Curavial; DPX-5648; DPX5648; DPX 5648; Oust; Oust XP; SMM; Sulfomethuron-methyl; Sulfometuron methyl ester; Methyl-2-((((4,6-dimethyl-2-pyrimidinyl)amino)carbonyl)sulfonyl)benzoate; Benzoic acid, o-((3-(4,6-dimethyl-2-pyrimidinyl)ureido)sulfonyl)-, methyl ester. CAS No. 74222-97-2. Pack Sizes: 1 g. Product ID: B0084-076243. Molecular formula: C15H16N4O5S. Mole weight: 364.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Tubulysin A | Tubulysin A is a novel antibiotic, which exhibits anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative activity. Tubulysins show very high cytotoxic activity against in vitro and in in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotherapeutics. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: TubA; (αS,γR)-γ-[[[2-[(1R,3R)-1-(Acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-benzenepentanoic Acid. CAS No. 205304-86-5. Pack Sizes: 1 mg. Product ID: BBF-03429. Molecular formula: C43H65N5O10S. Mole weight: 844.07. Custom synthesis is available. Send your inquiries for more information. | London |
| Virginiamycin S1 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Group: Pharmaceutical. Alternative Names: Staphylomycin S; Staphylomycin S1; Antibiotic 1754Z3B; Virginiamycin factor S; NSC177858; Stephylomycin; Eskamicin; Cebin V; Factor S; Glycine, N-[(3-hydroxy-2-pyridinyl)carbonyl]-L-threonyl-D-2-aminobutanoyl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-2-piperidinecarbonyl-L-2-phenyl-, r-lactone. CAS No. 23152-29-6. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03472. Molecular formula: C43H49N7O10. Mole weight: 823.89. Custom synthesis is available. Send your inquiries for more information. | London |
| X-396 | X-396 is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development. ALK is not expressed in healthy adult human tissue but ALK dysregulation and gene rearrangements are associated with a series of tumors; ALK mutations are associated with acquired resistance to small molecule tyrosine kinase inhibitors. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: X-376; (R)-6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-N-(4-(4-methylpiperazine-1-carbonyl)phenyl)pyridazine-3-carboxamide; 3-Pyridazinecarboxamide, 6-amino-5-((1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-N-(4-((4-methyl-1-piperazinyl)carbonyl)phenyl)-; 6-Amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-{4-[(4-methyl-1-piperazinyl)carbonyl]phenyl}-3-pyridazinecarboxamide. CAS No. 1365267-27-1. Pack Sizes: 25 mg. Product ID: B2693-462239. Molecular formula: C25H25Cl2FN6O3. Mole weight: 547.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Ximelagatran | Ximelagatran, an ester prodrug of melagatran, with anticoagulant effect, is the first member of direct thrombin inhibitors that can be taken orally. Uses: An orally active direct thrombin inhibitor; prodrug of melagatran. antithrombotic. Group: Pharmaceutical. Alternative Names: H 376-95; H 376/95; H 37695; H-37695; H37695; N-[(1R)-1-Cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyamino)iminomethyl]phenyl]methyl]amino]carbonyl]-1-azetidinyl]-2-oxoethyl]glycine Ethyl Ester; Exanta; H 376/95. CAS No. 192939-46-1. Pack Sizes: 5 mg. Product ID: B0084-264384. Molecular formula: C24H35N5O5. Mole weight: 473.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Zidebactam | Zidebactam is a β-lactamase inhibitor which possesses intrinsic antibacterial activity. Zidebactam is undergoing clinical development for the treatment of carbapenem-resistant Gram-negative infections. Uses: Bacterial infections. Group: Pharmaceutical. Alternative Names: WCK-5107; WCK 5107; WCK5107; Zidebactam; (1R,2S,5R)-7-oxo-2-(2-((R)-piperidine-3-carbonyl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate. CAS No. 1436861-97-0. Pack Sizes: 10 mg. Product ID: B2693-475437. Molecular formula: C13H21N5O7S. Mole weight: 391.4. Custom synthesis is available. Send your inquiries for more information. | London |
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